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Free Books / Health and Healing / Treatise On Materia Medica / | ![]() |
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Trichlorphenol |
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This section is from the "A Practical Treatise On Materia Medica And Therapeutics" book, by Roberts Bartholow. Also available from Amazon: A Practical Treatise On Materia Medica And Therapeutics
A preparation of much promise and which has yielded good results is that named trichlorphenol. It is produced by a combination of chlorinated lime and carbolic acid. A saturated solution of chlorinated lime is treated with a saturated solution of carbolic acid. Trichlorphenate of calcium is a product of the reaction, and remains in solution held by the chloride of calcium, another product. If to this solution some hydrochloric acid is added, the trichlorphenol is precipitated.
A method of extemporaneous preparation for merely topical uses-consists in the following: One pound of a solution of carbolic acid, four per cent in strength, is mixed with five pounds of solution of chlorinated lime and then filtered. If, for some purposes, this solution is too strong, it can be diluted with boiling water to the required strength.
According to Diannin, who first proposed this preparation, it has an antiseptic power twenty-five times greater than carbolic acid, and far exceeds thymol, salicylic acid, and chlorinated lime. It has proved highly effective in erysipelas, the solution painted over several times a day (Yurinsky). A one-per-cent solution has also been successfully used in the treatment of ulcers (Butckik). Other testimony has been published as to its utility in erysipelas, as an injection in leucorrhoea and in dysentery. On the other hand, Dr. Thomaschewsky has been disappointed in his clinical trials, finding it inferior to iodoform. The truth, as is usual under these circumstances, probably lies in the means.
 
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