For a start, it has been proven that germs and viruses do not cause cancer. Present cancer research is working on the supposition that cancer is caused by toxins of various kinds which one way or another find their way into the body and in some locations cause damage to the nucleus of a cell, turning it into a cancer cell. The presumption is that a gene within the DNA structure of the cell becomes altered so that the cell begins to multiply. Such a change to the cell's DNA is called a mutation. Also suspected of being able to cause cancer in this way are various forms of radiation, and any substance or influence that either causes cancer or tends to cause cancer is called a carcinogen. This hypothesis is a simple one, and if it were true it should be easy to prove, but although it is well known that certain substances can be carcinogenic, they are not always so, and the mechanism by which they are supposed to work has never been demonstrated. The hypothesis therefore remains only guesswork, and in the minds of most doctors cancer remains a mystery.

However, there is a theory on the causation of cancer which has been proven--one which accords to all known facts and biological laws and has been demonstrated in the laboratory. This theory, called the De-differentiation Theory of Cancer, developed from knowledge accumulated about how aerobic cells generate energy by the respiration of oxygen, and is best explained in the books of four of the 20th Century's greatest medical scientists: Dr Otto Warburg, Dr Max Gerson of Germany, Dr William F. Koch of the USA, and Dr Cornelius Moerman of Holland.

Dr Otto Warburg (1883-1970) was Director of the Max Planck Institute of Cell Physiology in Germany. The holder of many international honors, Dr Warburg was considered by Dr Dean Burk, head of the Cytochemistry Department of the US National Cancer Institute at the time, to be the world's greatest biochemist. In 1931 Warburg won the Nobel Prize in Medicine for his discovery of the oxygen transferring enzyme of cell respiration, and was voted a second Nobel Prize in 1944 for his discovery of the active groups of the hydrogen transferring enzymes. Conferred honorary degrees by the universities of Harvard, Oxford and Heidelberg, he was a member of the Royal Society of London, a Knight of the Order of Merit founded by Frederick the Great, and was awarded the Great Cross with Star and Shoulder Ribbon of the Bundesrepublik. Although Jewish, he was unmolested by the Nazis, and in the subsequent invasion of Germany by the Russians he was accorded protection and special consideration by the Russian High Command. Warburg's research spanned more than sixty years, and he was the author of over 500 published research papers and five books. His description of the experiments in which he transformed normal cells into cancer cells was contained in his lecture at the meeting of Nobel-Laureates on 30 June 1966 at Lindau, Germany. This lecture, titled "The Prime Cause and Prevention of Cancer", was reproduced in English by Dr Dean Burk and published by Konrad Triltsch, Wurzburg, Germany.

Dr Dean Burk (1904-1988) was a foundation member of the US National Cancer Institute and former head of its Cytochemistry Department. For his work in cancer research he received honors from France, Britain, Germany and Russia. Formerly Associate Professor of Biochemistry, Cornell University, he worked in cancer research at the Kaiser Wilhelm Institute in Germany and at the USSR Academy of Science, Moscow. Dr Burk was the recipient of the Domagk Prize for cancer research, a Knight Commander of the Medical Order of Bethlehem, and a Knight of the Mark Twain Society. He was co-author of the books Cancer, Approaches to Tumor Chemotherapy and Cell Chemistry and author of over 250 published scientific papers. Dr Warburg said Burk's outstanding and decisive discoveries in cancer research were:

  1. the metabolism of the regenerating liver (1941);
  2. that the malignancy of cancer was proportional to the fermentation rate of the cells (1956); and
  3. that in vivo growing hepatomas produced in vivo by carcinogens were similarly more malignant the higher the fermentation rate (1964).

Dr Max Gerson (1881-1959) was Jewish but didn't enjoy Warburg's standing. He was forced to flee Germany in 1933, spending the last twenty odd years of his life working in the USA. Best known for his successful dietary treatment of migraine, lupus, tuberculosis, diabetes and cancer, Gerson was the author of more than fifty published research papers and four books. Whereas Warburg was supported and honored for his full-time research, Gerson's great work was ignored by the medical establishment. He worked alone devoting his efforts mainly to the treatment of his patients, most of whom had been given up as hopeless cases by other doctors. Under Gerson's care, Dr Albert Schweitzer, double Nobel Laureate, completely eliminated his diabetes and Schweitzer's wife her tuberculosis using Gerson's dietary methods. After Gerson's death Dr Schweitzer said of him: "I see in him one of the most eminent geniuses in the history of medicine." Notwithstanding recognition by such medical greats as Dr Schweitzer and Dr Ferdinand Sauerbruch, Gerson's work received no recognition by the medical establishment, which considered him an unorthodox threat to the medical system.

William F. Koch, BA MA Ph.D MD, was Instructor in Histology and Embryology at the University of Michigan from 1910-14, Professor of Physiology at the Detroit College of Medicine from 1914-19, and Director of the Koch Cancer Clinic from 1919-49. Like Gerson, Koch was considered unorthodox and a threat to the established medical system, and despite adoption of his methods by independent doctors in the USA and Canada, he was continually persecuted by the American Medical Association, run at the time by a criminal who called himself Dr Maurice Fishbein but whose medical credentials were false. (Fishbein's dictatorial control of American medicine finally ended when he was kicked out at the AMA Convention in Atlantic City on 6 June 1949.) Koch was author of numerous publications concerned primarily with the biochemistry of immunity and of cancer, his best-known book being The survival factor in neoplastic and viral diseases: an introduction to carbony published in 1961. Dr Willard Dow, founder of the Dow Chemical Company, described Dr Koch as the greatest biochemist of the age and so far ahead of his contemporaries that they could not understand him.

Dr Cornelius Moerman graduated in medicine in 1930 and since then has devoted his entire professional life to cancer research and treatment. His theory of cancer, which he called the Metabolism Theory, he developed independently, but because his reasoning was based on the new knowledge about the respiratory processes of cells and the enzymes necessary for their accomplishment, his conclusions of course inevitably coincided with those of Warburg, Gerson and Koch. The English translation of his book A solution to the cancer problem was published in 1962 by The International Association of Cancer Victims and Friends Inc., Los Angeles.

Although doctors Gerson, Koch and Moerman each separately arrived at the same conclusion and demonstrated the theory by their successful treatment of human patients, it was Dr Warburg who demonstrated visually in the laboratory the actual changing of normal cells into cancer cells.

In fact, Dr Warburg was not the first to demonstrate that cancer arose from cells whose normal respiration had been disturbed. P.G. Seeger had proven this in 1936, 1937 and 1938 but it was F. Windisch in 1947 who succeeded in changing normal cells into cancer cells by intermittently withholding oxygen from them, an experiment repeated in 1953 by H. Goldblatt and G. Cameron. Dr Warburg's experiments, however, actually measured the degrees of respiration and fermentation involved in the transformation of cells, and actually measured the oxygen pressures inside tumors in the living body.

Dr Warburg did not physically interfere with the experimental healthy cells in any way, and he did not employ chemicals, heat or radiation--he merely reduced their supply of oxygen. When he reduced the oxygen needed by the cells for normal respiration by thirty-five per cent, they de-differentiated to become cancer cells.

How can cells in the human body with an unrestricted air supply be deprived of oxygen? Answer: toxemia (unhealthy blood).

Blood carries oxygen to the body's cells together with the nutrients the cells need to utilize the oxygen (the vitamins and minerals from which respiratory enzymes are made). Unhealthy blood is low both ways and sluggish in its flow. Dr Warburg's experiment in the laboratory took only days, but in real life cancer may take years, maybe few, maybe many, depending on the degree of toxemia, but when the critical point is reached the end result is the same.

Thus cancer, as with heart disease, can to a large extent be predicted just by observing a person's dietary and other living habits. A proper blood test which took into account blood viscosity and oxygen levels as well as the usual factors would be more precise. As previously explained, in conditions of toxemia before symptoms of impending disease become apparent, there appear in the blood microorganisms which increase in numbers as the milieu interieur further deteriorates. These are the pleomorphic microbes described in Chapter 5. The relationship between this indicator of toxemia and the subsequent incidence of cancer was observed in a study of twenty-five patients over a twenty-year period by Dr Guy Owens, a surgeon in Amarillo, Texas. He said in 1979:

"We selected 25 cases from my practise where the organism was repeatedly found during blood counts. They were run of the mill office cases, being male, female, old and young, but apparently in average good health. Over a 20 year period, 23 of these people came down with malignancy of one kind or another . . . proven by surgery and proper pathologic examination. Two cases were lost from our records although one was known to have died from an obscure abdominal condition."

It is easy to understand why researchers concentrating on studying one disease can easily be led to false conclusions having identified a microbe present at the scene, and why the cancer/virus controversy went on for years. However, Dr Owens knew that all people carry within them these organisms and that it was their multiplication and behavior that indicated a pathological condition. What he did not know was how the pathological condition caused normal body cells to change into cancer cells.