Cucurbita pepo, Linne'. The dried ripe seed of cultivated varieties with not more than 5 p.c. broken or defective seeds, or foreign organic matter.

Habitat. Tropical Asia, America; cultivated.

Syn. Pumpkin Seed, Pumpkin, Pompion, Cold Seeds Semen Peponis, Semina Cucurbitae; Br. Cucurbitae Semina Praeparata; Fr. Semences d Potirons; Ger. Kurbissamen.

Cu-cur'bi-ta. L. See etymology, page 597, of Cucurbitaceae.

Pe'po. L. Fr. Gr...., pumpkin, old form, pompon, lit. cooked by the sun, ripe, mellow -- i.e., not eaten until ripe.

Plant

Trailing annual; stem rough, hollow, hairy 3-9 M. (10-30 degrees) long, tendrils branched; leaves large, .25 -.5 M. (10-20') long, 15-30 Cm. (6-12') wide, obtusely cordate, hispid, palmately 5-lobed, serrate, petioles 7.5-20 Cm. (3-8') long; flowers July, large, 5-12.5 Cm. (2-5') wide, yellow, bell-shaped, monoecious, axillary; anthers 3, syngenesious; fruit Oct., large, round, oblong, smooth, fleshy, yellow, furrowed, .25-.5 M. (10-20') in diameter. SEED, broadly elliptical, ovate, 15-23 Mm. (3/5-5/6') long, 6-9 Mm. (1/4-3/8') broad, 2-3 Mm. (1/12-1/8') thick; yellowish-white, smooth, occasionally with thin transparent fragments of adhering pulp, shallow groove parallel to and within 1 Mm. (1/25') of the margin; fracture short, seed-coat consisting of a white coriaceous outer layer and a membranous inner layer (sometimes dark green; embryo whitish, straight with small conical hypocotyl and 2 plano-convex cotyledons; slightly odorous when contused; taste bland, oily.

Powder

yellowish-white, -- epidermal cells, stone cells, parenchyma cells, endosperm cells with aleurone grains, cotyledons with cells containing fixed oil and many small aleurone grains; integuments 21 p.c., kernel 79 p.c. Solvent: alcohol. Dose, 3j-2 (30-60 Gm.).

Constituents

Resin (yielding phytosterin, etc.), .5 p.c. Fixed oil 30 p.c., proteins (myosin, vitellin), cucurbitine (?), salicylic acid, sugar, ash 3-4 p.c.

Resin. -- Probably the active principle, residing in the tegmen or embryo, obtained by treating the seed, after the removal of fixed oil, with alcohol, ether, chloroform; it is soft, greenish-brown, acrid, bitter. Dose, gr. 15 (l Gm.).

Fixed Oil. -- Claimed to possess 3 iv; 15 cc.) the medicinal power of the drug, due no doubt to the presence of some resin, and is obtained by expression, or by treating seed with benzin; consists of the glycerides of oleic, myristic, and palmitic acids. The seed-infusion saturated with sodium chloride precipitates myosin, and when CO2 is added vitellin separates, which behaves like egg-yolk (due to its contained vitellin); the protein is possibly its emulsionizing principle.

Preparations

(Unoff.): Fluidextract, dose, 3ss-1 (15-30 cc.). Emulsion (3ij-4; 60-120 Gm. fresh seed, deprived of testa, should be beaten into a paste with sucrose + water or milk Oj; .5 L.), dose, 3v (150 cc.) at 2-hour intervals beginning at 10 o'clock A.M. Patients should remain quietly in bed all day; on the night before, and also before breakfast, give saline purgative to remove mucus, and about 3-4 hours after the pint (.5 L.) has been taken administer castor oil 3j-2 (30-60 cc.). Should fast the day previous to taking the medicine.

Cucurbita Pepo. Pumpkin seed; entire and longitudinally divided, showing embryo.

Properties And Uses

Tenifuge, vermifuge, diuretic, valuable because of its freedom from taste and harshness of action, but has the disadvantage of uncertainty. Same treatment applies to tape- and lumbricoid worms.