This section is from the book "A Practitioner's Handbook Of Materia Medica And Therapeutics", by Thos. S. Blair. Also available from Amazon: A Practitioner's handbook of Materia Medica and Therapeutics.
Sanguinaria, Blood-root. In large doses (f.e., I5 I. ; ec. tr., I0 I.) a harsh emetic very seldom used. In moderate doses (i.e., 10 I.; ec. tr., I I.) a stimulating expectorant. It does not act well in these doses with children. With adults it is of value in atonic conditions of the lungs or bronchi, but should not be loosely prescribed in all manner of acute and chronic coughs.
In small doses (f.e., 1/4 I..; ec. tr., 1-6 I..; @, I I.) it is indicated when there is irritable cough with the air passages dry, hot, and swollen. Especially useful when there is a sense of constriction in the throat, with a raw, sore feeling. In chronic cough, with a dry throat and circumscribed redness of the cheeks, and also in nasal polypi with mucous discharges, it is a valuable drug. These small doses promote the activity of the stomach and liver, are alterative, and influence the respiratory system in an eminently satisfactory manner. We have long been giving sanguinaria in doses entirely too large, and have failed to appreciate its great value. The nitrate of sanguinarine, in I gT. tablet triturates of the 3x, is an admirable way to give small doses.