Celandine, Chelidonium majus. A plant of complex composition. Its juice is exceedingly acrid and is an irritant sometimes used in the removal of corns and warts. Internally it is an unreliable drastic purgative in full doses; and it is apt to induce great cerebral disturbance. This drug was formerly official (U. S. P., 1890) and in the old Edinburgh Pharmacopeia, but it has been largely abandoned as a remedy.

In small doses (fl. 2 to 3 minims) it possesses a certain value in the treatment of jaundice and acute and chronic hepatitis not due to organic lesions.

Adequate personal experience leads me to consider the drug as one suitable for long-continued administration in functional diseases of the liver, especially those apt to result in gall-stone formation. There are few cholagogues that may be given for any length of time without deranging digestion, but this one may be so administered. In my hands, it cooperates well with sodium phosphate; but it must be regarded as a minor drug. Its use in full dosage is not at all justified, and in small doses it is slow in action.