Formula

C6H7N.

Derivation

Chinoline was first obtained from coal tar, but afterward from the cinchona alkaloids. More recently it has been produced by the action of glycerin on aniline, or nitro-ben-zol. It is an oily liquid, with highly refracting property, and it combines with acids to form salts. The salt, Tartrate of Chinoline, is not so deliquescent as the other salts formed by its combination with acids, and is in the form of lustrous crystals, which preserve their form even in a damp atmosphere, although they are soluble in water. Chinoline is very soluble in alcohol, and sparingly soluble in water.

Medical Properties And Action

Chinoline, like other phenol derivatives, such as resorcin, hydroquinone, etc., possesses the power to lower fever heat, but does not affect the normal temperature.

Therapeutic Uses

Like resorcin, chinoline has been used in intermittent and remittent fevers with great success; also in septic disorders. Topically, chinoline is a valuable antiseptic, and successfully acts upon minute organisms, preventing their increase and septic decomposition. A five per cent solution of the tartrate of chinoline, the salt generally employed, has been applied locally in diphtheria, with marked effect.

Dose

Of chinoline, gr. v to xv.

Dental Uses

Chinoline is used in dental practice as an antiseptic, belonging to the same class as resorcin, the salt tartrate of chinolin, in the form of a five per cent solution, being preferable for local application. It is also used in combination with carbolic acid, for application on cotton to an aching cavity from which a tooth has been extracted.