Acetanilid is made by treating aniline with glacial acetic acid in the presence of heat, with purification of the residue by sublimation and recrystallization.

Properties:

Form ................................

Solubility:

Feel .................................

Hot H2O .......................................................................................

Color ..................................

Cold H2O ....................................................................................

Odor ....................................

C2H5OH .......................................................................................

Taste ................................................

Tests showing some incompatibilities:

Triturate with Resorcinol ......................................

Con. KOH ................................................................................................

Con. HNO3 ..........................................................

Tinct. Ferri Chloridi .....................................................................

Therapeutics. - Acetanilid has had wide use in the past as a sedative and analgesic, being used to lessen the pains of neuralgia and rheumatism, but it is rather dangerous through its depressant action on the heart; this untoward property also interferes with its utility as an antipyretic. Dose, 0.2 Gm.

Two closely related products are: Acetphenetidinum and Antipyrina. Dose of each, 0.3 Gm.

Properties:

Acetphenetidin:

Antipyrin:

Appearance..........................................................................................

Appearance........................................................................................

Color .........................................................................................................

Color .........................................................................................................

Odor .........................................................................................................

Odor .........................................................................................................

Taste .........................................................................................................

Taste .......................................................................................................

Solubility:

Solubility:

H2O......................................................................................................

H2O......................................................................................................

C2H5OH .......................................................................................

C2H5OH......................................................................................

Incompatibilities and therapeutic indications similar to Acetanilid; Acetphenetidin is probably less dangerous.