This section is from the book "Laboratory Manual Of Pharmacology", by A. D. Bush. Also available from Amazon: Laboratory manual of pharmacology.
Saccharin is "the anhydride of ortho-sulphamide-benzoic acid"; it is a laboratory product of toluene.
Properties:
Appearance......................................................................................... | Solubility: |
Color............................................................................................................. | Cold H2O .................................................................................. |
Odor..................................................................... | Hot H2O ....................................................................................... |
Taste, 1 to 10,000 sol................................................................... | C2H5OH....................................................................................... |
NH4OH ........................................................................................ |
Add 0.06 Gm. citric acid to a 1 to 10,000 solution Saccharin, and compare relative sweetness with that first tasted..................................................................................................................................................................
Incinerate 0.008 Gm. Saccharin. What odor evolved?..............................................................................
Benzosulphinide is used as a substitute for sugar in cases of diabetes, but frequently is not tolerated very long.
The official Sodii Benzosulphinidum is more soluble.
 
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