This section is from the book "Laboratory Manual Of Pharmacology", by A. D. Bush. Also available from Amazon: Laboratory manual of pharmacology.
The official Cresol is a purified mixture of those isomeric cresols distilled from coal-tar at temperatures varying between 1900 C. and 2050 C.
Properties: Appearance...................................................... Color ..................................................................... Odor .....................................................................
Appearance when mixed with water..................................................................................................................................................
Cresol is an antiseptic of value, but is more readily used in the form of the official Liquor Cresolis Compositus. Prepare this compound as follows:
In a tared vessel heat 30 Gm. linseed oil over a water bath to a temperature of 70 ° C. In the meanwhile dissolve 8 Gm. KOH (or 5.4 Gm. NaOH) in 5 mils H20, warm to 700 C, add to the linseed oil, and mix thoroughly; then add 3 mils alcohol, continuing to heat the mixture, without stirring, until emulsification is complete. Then add 50 Gm. Cresol, mix thoroughly, maintaining temperature at 700 C, until a clear solution is produced. Finally, add enough water to make the finished product weigh ioo Gm.
Properties of Liquor Cresolis Compositus:
Appearance........................................................................................... | Solubility: |
Color ................................................................. | H20...................................................................................................... |
Odor.............................................................................................................. | Appearance of solution .................................................. |
Taste............................................................................................................ |
Liquor Cresolis Compositus is used as an antiseptic wash in the strength of a 5% solution in sterile water.
 
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