Pilocarpus consists of the dried leaflets of Pilocarpus Jaborandi, and P. microphyl-lus, (Fam. Rutacece), woody shrubs native to Northeastern Brazil. From its principal alkaloid, pilocarpine, are prepared two official salts, the Hydrochloride and the Nitrate, the former being preferable because of its greater solubility.

Properties of P. Hydrochloride:

Appearance ............................................................

Odor ... ....................................................

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Solubility: H20, 1 in 0.3; C2H5OH, 1 in 3. Hygroscopic in air. Characteristic test for Pilocarpine: Dissolve 0.005 Gm. Pilocarpine Hydrochloride in 2 mils distilled water, add 2 mils slightly acid solution H202; then add a thin layer of benzene. Next add 3 drops 0.3% solution K2Cr2O7. Shake mixture gently.

The benzene layer becomes a.......................................................color, while the aqueous layer remains yellow.

Pilocarpine has been recommended as a powerful sudorific in grave emergencies like uraemias and renal dropsy. Dose, 0.005 Gm. hypodermically. On the eye it has a myotic effect similar to that of physostigmine.