Properties and Uses. - Mercury - stimulant, alterative, tonic, antiphlogistic, sorbefacient, not directly a cholagogue, causes salivation; the liver retains it longest. Used in meningitis, bronchitis, pleuritis, pneumonitis, dysentery, rheumatism hydrocephalus, ascites, hydrothorax, dropsy, intestinal obstruction, malarial enlargement of spleen, smallpox. Plaster - applied to syphilitic nodes, glandular engorgements, enlarged spleen, to cover face in smallpox. It not only gives support, but is also a counter-irritant, while the mercury is absorbed and exerts a constitutional effect. Mercury with Chalk - similar to blue mass, only much weaker. Give to children deficient in biliary secretion, indicated by clay-colored stools, bowel complaints, diarrhoea, alterative to constitutional syphilis; the chalk is antacid. Blue Mass - sialagogue, alterative, irritant, cathartic; for the first two give gr. 3 (.2 Gm.) nightly or on alternate nights, following in the morning with a laxative; for the last give gr. 5-15 (.3-1 Gm.), at night and follow in the morning with a more active purgative; useful to increase liver and pancreas secretions. Mercurial and Blue Ointments - excellent externally, get resolvent effect by rubbing either upon the swollen or affected parts, and also a constitutional influence. Used in syphilis, when daily inunctions should be made under arms, flanks, thighs, chest, etc., swellings, glandular enlargements, engorged liver, spleen, inflamed joints, orchitis, smallpox eruption, erysipelas, prurigo pudendi, warts, and condylomata. Mercuric Nitrate Ointment - stimulant, alterative, similar to ointments of ammoniated mercury and red mercuric oxide, more stimulating than the former, often occasions salivation; eczema, Tinea capitis, impetigo larvalis, psoriasis, pityriasis, psorophthalmia, and inflammation of eye, eyelids, etc.
Hydrargyri Iodidum Flavum. Yellow Mercurous Iodide, Hgl. - (Syn., Hydrarg. Iod. Flav., Mercurous Iodide, Protoiodide of Mercury, Yellow Iodide of Mercury, Hydrargyri (Proto-ioduretum) Iodidum Viride, Ioduretum Hydrargyrosum; Fr. Proto-iodure de Mercure, Iodure mercureux; Ger. Quecksilberjodid (jodur). Gelbes Jodqueck-silber.)
Manufacture: Mix nitric acid and distilled water each 20 Ml. (Cc), cool, pour it upon mercury 50 Gm., after reaction separate, drain, and dry crystals (HgNO3 + H2O); dissolve 40 Gm. in distilled water 650 Ml. (Cc.) + nitric acid 6 Ml. (Cc), to which add slowly, with stirring, potassium iodide 16 Gm. dissolved in distilled water 32 Ml. (Cc), wash well and dry precipitate - 6Hg + 8HNO3 = 6Hg(NO3) + 4H2O; 2Hg(NO3) + 2KI = 2HgI + 2KNO3. It is a bright yellow, amorphous powder, odorless, tasteless, on exposure to light greenish in proportion as it decomposes into metallic mercury and mercuric iodide; insoluble in alcohol, ether, almost insoluble in water; contains 99 p. c of pure salt. Tests: 1. Slow moderate heat - orange, red, but yellow on cooling; quick strong heat - partially decomposes into mercury and mercuric iodide, finally volatilizes with residue .2 p. c 2. Heat with dried sodium carbonate (1) in dry glass tube - sublimate of metallic mercury. 3. Heat with sulphuric acid + little manganese dioxide - iodine vapor evolved. Impurities: Mercuric iodide, etc Should be kept dark, in well-closed containers. Dose, gr. 1/6-1 (.01-06 Gm.), ter die, gradually increased until trebled, provided salivation or diarrhoea does not occur.
Properties and Uses. - In advanced constitutional syphilis, being by many considered the best salt for this disease.
Hydrargyri Chloridum Corrosivum. Corrosive Mercuric Chloride, HgCl2. - (Syn., Hydrarg. Chlor. Corr., Bichloride of Mercury, Corrosive Sublimate, Mercuric Chloride, Perchloride of Mercury, Chloru-rctum (Chloretum) Hydrargyricum; Br. Hydrargyri Perchloridum; Pr. Deuto-chlorure de Mercure, Chlorure mercurique; Ger. Hydrar-gyrum bichloratum, Quecksilberchlorid, Sublimat.)
Manufacture: Sublime an intimate mixture of powdered mercuric sulphate and sodium chloride, when the two volatile elements, Hg, Cl, pass over and condense in the cooler as mercuric chloride - HgSO4 + 2NaCl = HgCl2 + Na2SO4; or may add a small portion of manganese dioxide to insure full liberation of chlorine and prevent the formation of mercurous chloride - HgSO4+2NaCl+MnO2 = HgCl2+ Na2SO4 + MnO2. It is in heavy, colorless, rhombic crystals, crystalline masses, white powder, odorless, characteristic, persistent metallic taste (use great caution in tasting), permanent, soluble in water (13.5), boiling water (2.1), alcohol (3.8), boiling alcohol (1.6), glycerin (12), ether (22), fuses to colorless liquid at 265° C. (509° F.), volatilizes in dense white vapors at 300° C. (572° P.), leaving residue .1 p. c; aqueous solution (1 in 20) acid, but neutral upon adding sodium chloride; contains 99.5 p. c. of the salt. Tests: 1. Aqueous solution with ammonia water - white precipitate; with excess of hydrogen sulphide - black precipitate; with potassium iodide T. S. - red precipitate, soluble in excess of reagent; with silver nitrate T. S. - white precipitate, insoluble in nitric acid. 2. Dissolve (fine powder) in ether or alcohol - undissolved residue .5 p. c. Should be kept in well-closed containers. Dose, gr. 1/50-1/8 (.0013-.008 Gm.), after meals, in bread pill; as antiseptic dressing the solution (1 in 1000-2000) is valuable.
Incompatibles: Alkalies, their carbonates, potassium iodide, lime water, tartar emetic, lead acetate, silver nitrate, albumin, soap, tannin.
Preparations. - 1. Toxitabellae Hydrargyri Chloridi Corrosiri. Poison Tablets of Corrosive Mercuric Chloride. (Syn., Toxitabel. Hydrarg. Chlor. Corr., Corrosive Sublimate Tablets, Bichloride Tablets.)
Manufacture: By compressing equal quantities (7.5 gr. (.5 Gm.)) of corrosive mercuric chloride and sodium chloride, colored blue, preferably with sodium indigotindisulphonate. Tablets must be of angular shape (not discoid), and have stamped distinctly upon each the word "POISON," and the skull-and-cross-bones design; each must weigh gr. 15 (1 Gm.), and contain .45-.55 Gm. of corrosive mercuric chloride and the remainder chiefly sodium chloride; they must be dispensed