Cucurbita Pepo,

Linne.

The dried ripe seeds of cultivated varieties with not more than 5 p. c. of other substances.

Habitat. Tropical Asia, America; cultivated.

Syn. Pumpkin Seed, Pumpkin, Pompion, Cold Seeds, Semen Peponis, Semina Cucurbitse; Fr. Semences de Potirons; Ger. Kurbissamen. Cu-cur'bi-ta. L. see etymology, above, of Cucurbitaceae. Pe'po. L.fr.Gr.

Pepo Pepo 777

pumpkin, old form, pompon, lit. cooked by the sun, ripe, mellow - i. e., not eaten until ripe.

PLANT. - Trailing annual; stem rough, hollow, hairy, 3-9 M. (10-30°) long, tendrils branched; leaves large, .25-5 M. (10-20') long, 15-30 Cm. (6-12') wide, obtusely cordate, hispid, palmately 5-lobed, serrate, petioles 7.5-20 Cm. (3-8') long; flowers July, large, 5-12.5 Cm. (2-5') wide, yellow, bell-shaped, monoecious, axillary; anthers 3, syngenesious; fruit Oct., large, round, oblong, smooth, fleshy, yellow, furrowed, .25-5 M. (10-20') in diameter. Seeds, broadly elliptical, ovate, 15-23 Mm. (3/5-5/6') long, 6-9 Mm. (1/4-3/8') broad, 2-3 Mm. (1/12-1/8') thick; yellowish-white, smooth, occasionally with thin transparent fragments of adhering pulp, shallow groove parallel to and within 1 Mm. (1/25') of the margin; fracture short, seed-coat consisting of a white coriaceous outer layer and a membranous inner layer (sometimes dark green); embryo whitish, straight with small conical hypocotyl and 2 plano-convex cotyledons; slightly odorous when contused; taste bland, oily. Powder, yellowish-white; microscopically - epidermal cells, stone cells, parenchyma cells, endosperm cells with aleurone grains, cotyledons with cells containing fixed oil and many small aleurone grains; integuments 21 p. c, kernel 79 p. c. Solvent: alcohol. Dose, ℥j-2 (30-60 Gm.).

Constituents. - Fixed oil 30 p. c., proteids (myosin, vitellin), cucurbitine (?), salicylic acid, resin (yielding phytosterin, etc.) .5 p. c, sugar, ash 3-4 p. c.

Resin. - Probably the active principle, residing in the tegmen or embryo, obtained by treating the seeds, after the removal of fixed oil, with alcohol, ether, chloroform; it is soft, greenish-brown, acrid, bitter. Dose, gr. 15 (1 Gm.).

Fixed Oil. - Claimed to possess (3iv; 15 Ml. (Cc.)) the medicinal power of the drug, due no doubt to the presence of some resin, and is obtained by expression, or by treating seeds with benzin; consists of the glycerides of oleic, myristic, and palmitic acids. The seed-infusion saturated with sodium chloride precipitates myosin, and when CO2 is added vitellin separates, which behaves like egg-yolk (due to its contained vitellin); the protein is possibly its emulsion-izing principle.

Preparations. - (Unoff.): Fluidextract, dose, ℥ss-l (15-30 Ml. (Cc.)). Emulsion (℥ij-4; 60-120 Gm. fresh seeds, deprived of testa, should be beaten into a paste with sugar + water or milk Oj;

Fig. 401.   Cucurbita Pepo.

Fig. 401. - Cucurbita Pepo.

Pepo Pepo 779Fig. 402.   Pumpkin seed; entire and longitudinally divided, showing embryo.

Fig. 402. - Pumpkin seed; entire and longitudinally divided, showing embryo.

.5 L.), dose, ℥v (150 Ml. (Cc.)) at 2-hour intervals beginning at 10 o'clock A.M.

Patients should remain quietly in bed all day. On the night before, and also before breakfast, give saline purgative to remove mucus, and about 3-4 hours after the pint (.5 L.) has been taken administer castor oil ℥j-2 (30-60 Ml. (Cc.)). Should fast the day previous to taking the medicine.

Properties and Uses. - Taeniafuge, vermifuge, diuretic, valuable because of its freedom from taste and harshness of action, but has the disadvantage of uncertainty. Same treatment applies to tape- and lumbricoid worms.

Allied Plant:

1. Citrul'Lus Citrullus (Vulgaris) - Cucurbita (Cu'Cumis) Citrullus, Watermelon Seed

Citrul'Lus Citrullus (Vulgaris) - Cucurbita (Cu'Cumis) Citrullus, Watermelon Seed. S. Asia; cultivated. Fruit edible, very large; seed flat, ovate, 12 Mm. (1/2') long., blackish, marbled, or orange-brown, ungrooved, blunt on the edge, otherwise like pumpkin seed. Kernels contain fixed oil 7.4 p. c, petroleum benzin extract 19 p. c, proteids, sugar, resin (cucurbitol - closely related to grindelol and ipurganol); diuretic, taeniafuge, anthelmintic. Dose, 3ij-16 (8-60 Gm.).