Datura Fastuo'Sa Ial'Ba); India. Used there as a criminal poison; capsule small, subglobular, spinous, seeds yellowish-brown, triangular, rough. D. Met'el, Entire-leaved Thorn-apple, Africa, S. Asia; capsule and seeds like D. fastuosa (alba), leaves nearly entire, downy. D. sunguin'ea, Peru; large shrub, or tree, leaves nearly entire, downy beneath, flowers large, upper half of corolla yellow, lower half blood-red.
Fabia'Na Imbrica'Ta, Pichi. Peru, (Me. Plant 1.5-2 M. (5-6°) high, growing on rocky hill-tops, resembling somewhat the pines; the woody branches are used, being resinous, with aromatic odor and taste; contain fabianine, resin, volatile oil. Diuretic, tonic, cholagogue; chronic vesical catarrh, gravel, renal, urethral, or cystic calculi. Should not be used in organic disease. Dose, gr. 5-40 (.3-2.6 Gm.).
Nicotia'Na Tabac'Um, Tabacum, Tobacco. The commercial dried leaves, official 1820-1900; C. and S. America (cultivated). Coarse robust annual, 1-2 M. (3-6°) high; stem erect, unbranched, solid, green, hairy; root long, fibrous; flowers rose-color, calyx bell-shaped, hairy, viscid, corolla 4-5 Cm. (1 3/5 - 2') long, tubular, inflated; fruit ovate capsule, 2.5 Cm. (1') long, opening at summit; seeds many, reniform, reticulate, brownish. Leaves, about .5 M. (20') long, 10-15 Cm. (4-6') wide, ovate-lanceolate, acute, entire, waved, brown, friable, hairy; odor heavy, peculiar; taste nauseous, bitter, acrid. Plant not known to be wild, and leaves in curing undergo a sweating process (chemical change) by which odor is modified through generation of a new volatile principle, and amount of nicotine decreases owing to its volatility; contains nicotine .7-5-11 p. c. (colorless oily liquid), nico-
Fig. 361. - Nicotiana Tabacum.
teine (nicotia) 2 p. c, nicotelline, nicotimine, pirolidine (?), nicotianin (tobacco camphor), tannin, resin, gum, malates, citrates, ash 14-18-27 p. c. (Ca, K, NH4 - phosphates, sulphates, malates, chlorides, nitrates); solvents: alcohol, hot water. Narcotic, sedative, diuretic, emetic, diaphoretic, cathartic, antiseptic; first stimulates (causing convulsions) then paralyzes motor nervous system (spine), produces vomiting, purging, collapse, contracted pupils, depressed then increased heart action (rapid, feeble pulse), cold extremities, death by paralysis of respiration and heart; excessive use causes dyspepsia, diminished sexual power, nervousness, angina pectoris, and in the young impairs body nutrition. So severe as to be little employed as a medicine, but may be used to relax spasms, relieve local pain, constipation, spasmodic asthma, tetanus, as an enema in intussusception, strangulated hernia, impacted caecum, hemorrhoids, scabies, strychnine-poisoning. Poisoning: By tobacco or nicotine, give tannin, emetics, then strychnine (physiological antidote), alcohol, ammonia, digitalis, belladonna, iodides, artificial respiration, maintain recumbent position. Dose, gr. i-3 (.03-.2 Gm.); wine (vinum), 10 p. c, ev-60 (.3-4 ML (Cc.)); enema tabaci, 5 p. c; oleum tabaci (from distilling leaves - acrid, poisonous, dark brown oily liquid); aqueous extract, fluidextract, infusion ointment, poultice. N. rus'tica, Wild Tobacco, and N. quad-rival'vis, Canada, Eastern U. S. N. repan'da, Cuba. N. per'sica, Persia. N. rustica, cultivated in Turkey, India, etc. All may be used similarly.