On account of the power of lime salts to dissolve organic membranes, they have been recommended in chronic Bright's disease, and in post-scarlatinal albuminuria "to dissolve proteinous infiltrations of the kidney." Kuchenmeister reports cases treated by large doses of lime-water and soluble lime salts, with immediate and marked increase in the quantity of urine passed, and with corresponding subsidence of the dropsy. The amount of albumen was lessened, but sometimes slight hemorrhage occurred (Ranking, 1869; Rev. Med., February, 1870). His results have not been widely corroborated, but Baudon reports a case in which the iodide of calcium seemed to succeed after iodide of potassium failed; quinine and iron were given also (Practitioner, i., 1869).

From our knowledge of the styptic properties of lime salts, we should rather expect them to restrain renal hemorrhage than to cause it, and Stromeyer and Caspari report the value of the phosphate for this purpose.

Preparations And Dose

Liquor calcis: dose, 1/2 to 2 fl. oz. or more (contains 1/2 gr. to the ounce). Liquor calcis saccharatus: dose, 15 min. to 1 fl. dr. (contains 7.11 gr. to the ounce). Linimentum calcis (lime-water and olive-oil, equal parts). Creta proeparata: dose, 10 to 60 gr. Mistura cretoe: dose, 1 to 2 fl. oz. (contains chalk 1/4 oz., gum-acacia 1/4 oz., syrup 1/2 oz., cinnamon water to 8 oz.). Pulvis cretoe aromaticus: dose,

10 to 60 gr. (contains cinnamon, nutmeg, saffron, cloves, chalk, cardamoms, sugar). Pulvis cretoe aromaticus c. opio: dose, 10 to 60 gr. (contains 1 gr. of pulv. opii in 40). Calcii chloridum: dose, 2 to 10 gr. Vapor chlori (made with chlorinated lime). Calcis phosphas: dose, 2 to 20 gr. or more. Calcis hypophosphis: d to 10 gr. Besides these officinal preparations, there are many compounds such as the iodide, the bromide, and the carbolate of calcium of which the lime is the less active ingredient, and of which the properties are mainly those of iodine, bromine, etc. There are also many private preparations of lime, such as the lacto-phosphate, the compound syrup of the phosphates (Parrish), and others. A number of formulae for lime sucrates, hypophosphites, etc., are given in the Pharmaceutical Journal, June, 1877.

The sulphide of calcium is not officinal: convenient granules of it containing 1/10 gr. and up to 1 gr. are now prepared.

Various formulae for "phosphated bread" and natural forms of phosphate have been published. Superphosphate of lime 1/2 oz., carbonate of iron 1/2 oz., butter and sugar, of each 1/4 lb., flour 3/4 lb., treacle 1/2 lb., make 80 cakes (Medical Times, i., 1859). Acid phosphate of lime and moist carbonate of soda may be used as a good "baking powder" (Horsford, Ranking, ii., 1860). Chevrier has an aerated water containing tribasic phosphate (Pharmaceutical Journal, September, 1874). Dannecy recommends to wash and powder beef bones, and boil them for an hour with carbonate of soda and water, then to wash in a filter - to dry and sieve (Bulletin de Therapeutique, March 15, 1858).

[Preparations, U. S. P. - Calcii carbonas proecipitata; Cretoe proe-parata; Mistura cretoe: prepared chalk 1/2 troyounce, glycerin 1/2 fluid ounce, gum arabic 120 grains, cinnamon water, water, each 4 fluid ounces; Trochisci cretoe: prepared chalk 4 troyounces, gum arabic 1 troyounce, nutmeg 60 grains, sugar 6 troyounces, make 480 troches. Calcii chloridum; Calcii hypophosphis; Calcii phosphas proecipitata; Calx; Liquor calcis - lime-water; Linimentum calcis: lime-water 8 fluid ounces, flaxseed-oil 7 troyounces. Calx chlorinata - chlorinated lime.]