Good results have been obtained after surgical evacuation of a suppurating bubo, from injecting a weak solution of copper sulphate into the cavity. M. Danielli found this quickly diminish the secretion, which after simple opening is very apt to re-form (Bulletin de Therapeu-tique, 1868). M. Diday recommended a strength of 3 gr. to the ounce. The solid sulphate is a good application to syphilitic cracks, patches, and ulceration about the mouth and tongue.