M. Brassac, of the French naval service, records the best results from bismuth in epidemic dysentery. Finding little or no benefit from small doses, he followed the teaching of Monneret, and beginning with 230 to 300 gr. daily, increased to more than 1,000 gr.; he divided this into about five doses, according to the case, giving it in broth or milk, or sometimes by enema, and so long as more than one stool occurred in the day. This plan was very successful, and had no ill result; as a rule, his patients began at once to eat better and to gain strength (quoted Edinburgh Medical Journal, 1867). Trousseau also used bismuth injections in dysentery (Lancet, i., 1855), and more recently Dr. Houghton writes from Borneo, concerning their great value in subacute and chronic cases in tropical climates; he prescribes 30 gr. with mucilage to be injected two or three times daily, and retained if possible (Lancet, ii., 1879). In acute and chronic colitis, Laseque also used, with the best results, enemata of 30 to 150 gr. with egg or mucilage.