This section is from the book "Materia Medica And Therapeutics Inorganic Substances", by Charles D. F. Phillips. Also available from Amazon: Materia medica and therapeutics.
Trousseau has observed that the pain in the course of affected nerves, which is often severe and long persistent in the zoster of elderly persons, may be relieved by arsenical medication, though this will not cut short the course of the attack itself ("Clinical Medicine").
In Sycosis, non-parasitic in character, there is much evidence of the value of the drug, and this would accord with what we know of it in other cases of pus-formation. Dr. Laycock has used an arsenicated glycerin (2 dr. of Fowler's solution in 10 dr.) as a local application, with good results; it is somewhat strong, and acts as a "substitutive irritant" (Medical Times, ii., 1864).
Erysipelatous Inflammation of a phlegmonous typo is liable to give rise to sloughing, but if, at the first appearance of this change, small doses of arsenic be administered, together with a generous diet, the more severe results may be warded off, and even after sloughing has taken place, arsenic will often control it effectually.
In Hospital Gangrene the results obtained strongly incline me to consider it very beneficial. In twelve cases in which I have tried it, giving 4 to 10 min. of Fowler's solution every two or four hours, I was well satisfied with the result, especially as arsenic was the only active treatment used; no local caustics were needed. In various other affections of gangrenous character the same remedy has proved very reliable.