There is evidence of a favorable influence being exerted by salt in ague and some of its complications. Piory used it, and Gintrac gave 30 grammes daily with success except in quartans; he did not verify reduction of the spleen (Bordeaux, 1850), but Herschel and Rondelet have done so after a more prolonged use of the remedy. At Bruges, forty-eight cases were reported, and all of them, except the quartans, were convalescent in three to four days, after taking from 30 to 45 grammes of salt daily, freely diluted; it cleansed the furred tongue and improved appetite. Out of fifty-two cases reported from Africa the greater number were cured with 15-gramme doses of salt (Union Medicale, 1851), and Villemin states that, according to his experience at Damascus, common salt stopped attacks of ague six times out of every seven, 1/2-oz. doses being given two, three, or four times (Gazette Hebdom. de Med., March, 1854). Mareschkin, a Russian physician, has recently given further evidence to the same effect (Bulletin Generale de Thera-peutique, vol. li., p. 183).