Eighty years ago von Lobel, a physician, related his cure from an inveterate cranial neuralgia (which was accompanied with debility and failure of mental and sensory power) by an ethereal solution of the drug. He took 1/4 gr. every two hours, and (with one relapse) was restored to health in a short time, and after only a few doses. This experience was corroborated to some extent, and the remedy came into great repute, but was soon found to be a dangerous one and difficult to manage, and it gradually fell into disuse, no doubt owing to the largeness of the doses. A few years ago Mr. M. Bradley published a case of neuralgia of the chest-walls, rapidly cured by "tincture of phosphorus," after failure of all recognized remedies, and later he recorded other successful results (British Medical Journal, October, 1872). In the following year Dr. Slade King added testimony to its value in doses of 1/30 to 1/20 gr. (Medical Times), and Dr. Ashburton Thompson recorded forty consecutive cases either cured or relieved (Practitioner, 1873); Mr. Sanger, of Alfris-ton, referred to an equal number (British Medical Journal), and Dr. Hammond praised it in America (Practitioner, i., 1877).

Drs. Radcliffe and Broadbent may be cited also among those who early employed it with good results, the latter especially in "anginoid pain"- a cardiac neuralgia (Practitioner, 1875). It was found useful in cases connected with extreme general debility - whether from over-lactation, hemorrhage, or simple asthenia - in cases due to pregnancy, to cold, and to local irritation, such as carious teeth, and even to rectal cancer (Thompson). Anstie's experience was not so favorable.

I have myself seen much benefit from it in many of the above cases, also in uterine neuralgia occurring in sensitive patients, and induced either by protracted lactation, excessive sexual passion, or by mental or local causes. The severe pain is apt to come on just before or during the monthly period, and then 1/100 to 1/50 gr. should be given three or four times daily; during the interval the smaller dose should be given, and less frequently.