In irritation of the male genitals in plethoric subjects, with undue erections or excessive seminal losses, the bromides are often highly useful. They have a local anaesthetic effect when applied to the urethra, and when taken internally their value is evident rather in cases when sexual excitement is connected with local irritation and congestion, as haemorrhoids, ascarides, etc., than when there is mental or central causation. They tend to lessen, also, spinal congestion and reflex irritation. Berger finds, perhaps, the best results from camphor bromide in such cases (Medical Times, i., 1877, p. 264). When there is marked debility with anaemia, or when spermatorrhoea is unaccompanied by erections or sensations, bromides are not the best remedies.