This section is from the book "Materia Medica And Therapeutics Inorganic Substances", by Charles D. F. Phillips. Also available from Amazon: Materia medica and therapeutics.
Wetherby, of New York, records a very severe case of bleeding from the tonsil (cases which are specially anxious ones, on account of the proximity of the carotid) completely controlled by the application of Monsel's solution (Ranking, ii., 1866); and I have seen instances in which a large vessel must have been wounded by an incision in the tonsil, effectively treated by the local use of tincture of the perchloride; it should always be tried before more serious measures are commenced. As styptic applications to the bleeding surfaces of wounds, iron compounds are not so suitable as some others, because they necessarily prevent union by "the first intention," and they leave a coag-ulum, on the separation of which hemorrhage is apt to recur. Maison-neuve, however, performed some of his boldest and most brillant operations with their help; thus, he removed a growth occupying half the face and head, and involving numerous vessels, applying perchloride on pledgets of charpie at almost every stroke of the knife, and so that the weakened boy lost but little blood; a brown eschar formed, and separated about the twentieth day (Medico - Chirurgical Review, ii., 1856). Bour-gade applied perchloride to the bleeding surface immediately after all operations - calculating to render them by this means "as painless and as safe as if caustic had been used instead of the knife" - and to prevent septicaemia; the application was painful for a few hours, but not much pus formed, and granulation occurred in a healthy manner. He reports ninety-five cases (Union Medicale, 1867, No. 104). The perchloride is still thus used sometimes in operating upon soft tissues in anaemic subjects when hemorrhage is likely to be serious. I have seen it applied in the removal of a cancerous tongue and of a cancerous breast, and also in a thigh-amputation, and in each case secondary hemorrhage occurred, and I was not at all satisfied with the action of the styptic; further, it is not free from risk of causing embolism.
1 The original Monsel's solution was made with persulphate, as described by him (Recueil des Memoires, t. xvii., 1856, quoted by Buisson).