This section is from the book "Materia Medica And Therapeutics Inorganic Substances", by Charles D. F. Phillips. Also available from Amazon: Materia medica and therapeutics.
Bonnet recommended 5 to 10 drops daily in cases of glandular scrofulosis, conjoining local applications (Bulletin, 1837), but the internal use of bromine is practically superseded by that of its compounds. It is possible, however, that smaller and more frequent doses of bromine than have hitherto been prescribed might give better results, with avoidance of gastric irritation.
In various forms of struma, scrofula, and chronic conditions of blood-poisoning, sea-baths are indicated, and during convalescence from fevers and other acute disorders, or after prolonged town-residence or town-work, they have an excellent effect.
In the different manifestations of these constitutional states, such as enlarged glands, tumid abdomen, indolent ulceration, ophthalmia, etc., preparations of iodine, and especially the tincture, are of proved value. But though they lead to disintegration of morbid deposit, they do not appear to assist renovation of tissue, and for permanent good results require to be supplemented by good food and hygiene. Hence, also, the combination with iron - iodide of iron - is an excellent form, and the conjoint use of cod-liver oil is very desirable. These remedies are invaluable in rachitis especially, and are usually well borne by delicate children when alkaline iodides are not. Simon, indeed, concludes that the latter ought not to be given at all under two years of age (Medical Record, 1876), and even the iodide of iron sometimes excites gastric and renal irritation, especially in some delicate children with fair skin, red hair, and enlarged throat-glands, so that it is desirable to commence its use in small doses.
I have been accustomed to give 1 to 3 min. doses of iodine tincture well diluted, and continued for a considerable time, in cases of struma, and can recommend this form of medication. The iodide of ammonium is said sometimes to have exceptional value.
In the different forms of disease included under these headings, and characterized by enlarged or suppurating glands, irritable mucous membranes, caries, and swelling of knee and elbow joints, emaciation, etc., iron, although much lauded by Hufeland, is not so serviceable when given alone as are certain alteratives - iodine, lime, etc.- but when combined with such remedies it is of great value for the cachexia, anaemia, and torpor of the blood-forming glands, which are usual accompaniments; I have, indeed, found the iodide of iron to be an excellent remedy for most affections of a scrofulous type. The perchloride, as already mentioned, is a good external application for discharging glands. The vinum ferri, or an alkaline citrate with aromatics, is very useful in the mucous diarrhoea of rachitic children.