These conditions are sometimes advantageously treated by the method of Higginbottom, but the solution may be made weaker, and nitrous ether employed as the vehicle: it does not dissolve so much as water, but 30 to 40 gr. in the ounce will be strong enough; this should be painted over the affected finger, or the commencing boil, or the inflamed and irritable patch. Chilblains are relieved by it, and it is said to prevent a threatened eruption of herpes if used early enough. To bedsore, in any stage, a solution of 5 to 10 gr. in the ounce may be applied with advantage.