This section is from the book "Recent Materia Medica: Notes On Their Origin And Therapeutics", by F. Harwood Lescher. Also available from Amazon: Recent materia medica.
Salicylate of Phenol (Sahli) or Salicylate of phenyl (Moss). Phenyl Ether of salicylic acid. C13 H10 03 = C6 H4 OH COO (C6 H5.)
Prepared by heating together salicylate and phenate of Sodium with phosphoric chloride; first produced by Prof, von Nencki, of Berne, and reported on by M. Sahli, of Berne, in 1886.
Characteristics. A white crystalline powder, of slightly aromatic taste and smell: it probably contains about 60 % of Salicylic acid, and about 40 % of phenol. It is Salicylic acid in which one atom of Hydrogen is replaced by one of Phenyl.
Insoluble in water, soluble in alcohol, melting at 108° F.
Therapeutics. Is reported to act more powerfully than salicylic acid in acute rheumatism, not disturbing the digestive functions.
Has been used with success in cholera.
It is not dissolved in the stomach, but mixing with the pancreatic ferment in the duodenum, it is believed to split into its two original compounds, Salicylic acid and Phenol.
Dose: 15 to 30 grains, suspended in water or milk. Acute articular Rheumatism; 25 grains thrice a day, for adults; and 8 grains for children, four to six times a day. As an antipyretic, in doses of 30 grains three or four times a day.
"In sciatica, 8 grains in evening, and 16 grains at bed-time, give a good night." - Dr. Aschenbach, of Corfu, Pharm. Record, 1887, p. 230.
"In bowel complaints, and typhoid fever, as an internal antiseptic, 10 grains every three hours, most successful." - Dr. Gallet, of New York.
A strong antiseptic and germicide, and a disinfecting, deodorising mouth wash. Externally used like Iodoform to ulcers.
Di-iodo-Salol has been proposed for skin diseases.
 
Continue to: