The dried leaves of Datura Stramonium. Thorn Apple.

Characters. - Large, ovate, sinuous, deeply cut; of a heavy odour, which is strongest while they are drying, and of a mawkish, faintly bitter, nauseous taste.

Composition. - A very small proportion of daturine. The other constituents are chiefly saline and mineral matters.

Stramonii Semina, B.P.; Stramonii Semen, U.S.P. Stramonium Seeds, B.P.; Stramonium Seed, U.S.P

The dried ripe seeds of Datura Stramonium.

Fig. 212.   Stramonium seeds.

Fig. 212. - Stramonium seeds.

Characters. - Brownish-black, reniform, flat, rough; inodorous unless bruised, when they emit a peculiar, heavy smell.

Composition. - Contains an alkaloid, daturine, identical with atropine, and also some hyoscyamine.

Preparations.

B.P.

Dose.

Extractum Stramopii ..............................................................

1/4-1/2 gr.

Tinctura " ...........................................................

.10-30 min.

U.S.P.

Dose.

Extractum Stramonii ...........................................................................

1/2-gr.

" " Fluidum ............................................................

. 1 min.

Tinctura " .........................................................................

.10-30 min.

Unguentum " .........................................................................

Action and Use. - The impure alkaloid daturine, consisting of atropine and hyoscyamine, has exactly the same physiological action as atropine, though less powerful.

The chief use of stramonium is as an antispasmodic in cases of asthma. It is often employed in the form of cigarettes during the attack, or the fumes of the ignited powder are inhaled. A mixture of potassii nitras, potassii chloras, stramonium, and ipecacuanha has been employed with good effect in asthma by inhaling the fumes of the ignited mixture. The leaves of Datura Tatula have been substituted for Datura Stramonium.