Benzoyl -eugenol. - Origin. - From eugenol.

Description and Properties. - It occurs in neutral, odorless, colorless, acicular crystals, having a feebly bitter taste; soluble in hot alcohol, ether, and chloroform, and insoluble in water.

Dose. - Not yet determined.

Cinnamyl-eugenol. - Origin. - A derivative of eugenol.

Description and Properties. - Colorless, odorless, tasteless, lustrous needles, soluble in hot alcohol, ether, and chloroform, and insoluble in water.

Eugenyl-acetamide. - Origin. - Obtained from eugenol-acetic-ethyl-ether by treating with solution of ammonia. It occurs as a crystalline powder.

Physiological Action. - Externally and Locally. - Oil of cloves is a counterirritatant, local anesthetic, and germicide.

Internally. - Its action is essentially the same as that of anise, it being a powerful carminative and stimulant.

Therapeutics. - Externally and Locally. - Oil of cloves is employed as a local anesthetic in toothache, earache, and neuralgia, and as a synergist to other counterirritants, rubefacients, and antiseptics. The eugenol-acetamide is a powerful local anesthetic, being analogous to cocaine in its action.

Internally. - The therapeutics are similar to those of anise. The benzoyl-eugenol has been highly recommended by some practitioners as a valuable remedy in tuberculosis. The following combination may be employed as an antiseptic and antifermentative in gastric fermentation, to be administered either in soft capsules, with olive oil as a vehicle, or in the form of an emulsion:

R Olei caryophylli, Olei cinnamomi, Olei menthae piperitae, Creosoti, aa mj - M.

Sig. - Take at one time.

The better way to administer it is in the form of soft capsules, each capsule containing the above dose in about 6 minims (0.37 Cc.) of olive oil. One or two capsules should be given three times a day, after meals.