This section is from the book "Materia Medica Pharmacy, Pharmacology And Therapeutics", by W. Hale White. Also available from Amazon: Materia Medica Pharmacy, Pharmacology And Therapeutics..
The bark of the stem and root of Punica Granatum Linne (nat. ord. Lytkrariea).
India and Southwestern Asia; cultivated and naturalized in subtropical countries.
In the quills or fragments, from 5 to 10 cm. long, and from I to 3 mm. thick; outer surface yellowish-gray, somewhat warty, or longitudinally and reticulately-ridged; the stem-bark often partly covered with blackish lichens; the thicker pieces of the root-bark more or less scaly externally; inner surface smooth, finely striate, grayish-yellow; fracture short, granular, greenish-yellow; indistinctly radiate; inodorous; taste astringent, very slightly bitter.
The chief constituents are - (1) Pellctierine, C8H13NO, 1/2 per cent., a colorless, oily, aromatic alkaloid, soluble in water, Alcohol, Ether and Chloroform. (2) Three allied alkaloids, Methyl-, Pseudo-, and ispelletierine. (3) Punicotannic Acid, C20H16O13, 20 per cent.
Dose, 1/2 to 1 1/2 dr.; 2. to 6. gm.
Pomegranate is a powerful astringent, and the decoction B. P., 1 to 5; dose, 1/2 to 2 fl. oz.; 15. to 60. c.c may be used as a gargle for a sore throat. In large doses it is emetic and purgative. It is an anthelmintic for the tapeworm. It is so disagreeable that it is rarely used, but if employed the decoction may be given every hour for four hours before breakfast. A purge should be administered the night before and a few hours after breakfast. Pelletierine dose of tannate, (not official), 3 to 6 gr.; .20 to .40 gm. is the active anthelmintic principle, and is said to be very efficient for killing the common tapeworm. Large doses of pelletierine given to animals act like curare.