This section is from the book "Materia Medica Pharmacy, Pharmacology And Therapeutics", by W. Hale White. Also available from Amazon: Materia Medica Pharmacy, Pharmacology And Therapeutics..
Hops. - The strobiles of Ilumulus Lupulus Linne (nat. ord. Urticaceae).
Northern temperate zone; cultivated.
Ovate, about 3 cm. long, consisting of a thin, hairy, undulated axis, and many obliquely ovate, membranous scales, in the upper part reticulately-veined, and towards the base parallel-veined, glandular, and surrounding a subglobular achene; color of the scales greenish, free from reddish or brownish spots; odor, aromatic; taste, bitter, aromatic and slightly astringent.
The chief constituents are - (1) Lupulin. (2) Lupu-linic Acid, II per cent., a bitter crystalline principle. (3) Valerol, 1 per cent., an aromatic volatile oil giving the odor. (4) Resin, 9 to 18 per cent. (5) Tannic acid, 3 to 4 per cent.
Incompatibles. - Mineral acids, and metallic salts.
A glandular powder, separated from the strobiles of Humulus Lupulus Linne (nat. ord. Urticaceae).
Bright, brownish-yellow, becoming yellowish-brown, resinous, consisting of minute granules, which, as seen under the microscope, are subglobular, or rather hood-shaped, and reticulate; aromatic and bitter.
Dose, 5 to 30 gr.; .30 to 2.00 gm.
1. Extractum Lupulini Fluidum. - Fluid Extract of Lupulin. Lupulin, 1000; by maceration and percolation with Alcohol, evaporation and solution to 1000 parts.
Dose, 5 to 30 m.; .30 to 2.00 c.c.
2. Oleoresina Lupulini. - Oleoresin of Lupulin. Lupulin, 100; by percolation with Ether and evaporation. Dose, 1 to 5 gr.; .06 to .30 gm.
The volatile oil is stomachic and carminative like other volatile oils. To a slight extent it reflexly excites the circulation. The bitter principle aids the stomachic influence. Hops are decidedly soporific. Probably it is the volatile oil that produces this effect.
The pharmacopoeial preparations of hops are not much used, but good beer, because of the hops contained in it, may with some persons aid digestion, and for this purpose is often given with meals to those whose digestion is feeble after a long illness, or from any other cause. The alcohol in the beer increases this effect. Many people find the soporific influence of beer very well marked. Lupulin has been used in nervous tremors, wakefulness and in the delirium of drunkards.