This section is from the book "Materia Medica Pharmacy, Pharmacology And Therapeutics", by W. Hale White. Also available from Amazon: Materia Medica Pharmacy, Pharmacology And Therapeutics..
Theobromine Sodio-Salicylate. (Not official).- C7H7NaN4O2+NaC7H6O3=361.42. Synonym. - Diuretin.
Dose, 15 to 30 gr.; 1. to 2. gm.
This is a pure diuretic acting upon the renal epithelium, without action upon the heart, and it is believed that it does not irritate the kidneys. The daily dose is from one to two drachms; 4. to 8. gm., best administered in solution with aromatic water. It has been administered with benefit in cases of severe cardiac or hepatic dropsy. It is said that it does not produce depression, but it has occasionally given rise to severe symptoms, which may have been due to impurities.