This section is from the book "A Manual Of Practical Therapeutics", by Edward John Waring. Also available from Amazon: A Manual of Practical Therapeutics.
Cuspariac Cortex. AngusturAe Cortex. Cusparia or Angustura Bark. Obtained from Galipea Cusparia, St. Hil.; Galipea Officinalis, Hancock. Formerly attributed to Bonplandia Trifoliata. Nat. Ord. Rutaceae. Source, the tropical parts of South America. Native name of the tree, Orayuri; of the bark, Carony.
Med. Prop. and Action. Tonic, stimulant, and aromatic. It is best given in infusion, in doses of fl. oz. iss. - fl. oz. ij. In larger doses it induces nausea. Taken internally it promotes digestion, increases the appetite, expels flatus, and does not cause constipation. By some it is believed to possess anti-periodic properties. When chewed, it leaves for some time a sense of heat and pungency in the throat and fauces. Active principles, 1, a crystalline principle, which has been named Augusturine, and Cusparine: 2, a volatile oil; 8, a resin.
Offlc. Prep. Infusum CuspariAe (Cusparia in coarse powder oz. ss.; Distilled Water at 120° fl. oz. x. Infuse for two hours and strain). Dose, fl. oz. j. - fl. oz. ij.
Dose of Powdered Bark, gr. x. - gr. xl.
Incompatible with the Infusion. The Sulphates of Iron, Zinc, and Copper; Nitrate of Silver; Bichloride of Mercury; Salts of Lead; Tartar Emetic; Infusions of Galls and Catechu.
In Intermittent Fevers, it was at the time of its introduction (1788) considered equal, if not superior, to Cinchona. More recently, Mr. Brande * has spoken favourably of its febrifugic properties, and relates instances in which it proved successful. Alibert, however, gave it a fair trial, and found it of little value; and general experience has pronounced the same verdict. In South America, however, it has been much employed in the treatment of low malignant fevers occurring in marshy districts. (Garrod)
It does not oppress the stomach like some other tonics; and under its use the tone of the digestion often rapidly improves. Cinnamon is a good adjunct; and it maybe advantageously combined with • Rhubarb, Alkalies, &c.
In the Diarrhoea of Children, when the fAeces are loaded with mucus, it proves useful. Dr. Lettsom speaks highly of its efficacy.
1065. In Debility, Hysteria, or whenever a light tonic is indicated, Cusparia in infusion will be found efficacious.