Phosphate of Iron, 3 FeO, PO5, partially oxidated. A slate-blue amorphous powder, insoluble in water, soluble in Hydrochloric Acid. (Offic. Brit Pharm.)
* Ranking's Abstract, 1856, vol. xxiv. p. 104.
Cyc. Pract. Med., vol. iii. p. 237.
X Lancet, July 13, 1850.
§ See Med. Gaz., Oct. 15, 1841.
Ferri Perphosphas. Perphosphate of Iron. Ferri Oxy-phosphas. Ferri Sesqui-phosphas. Fernim Phosphoricum Album. White Phosphate of Iron (Fe2O3, 3 PO5 + 8 HO). A white tasteless powder.
Ferri Superphosphas. Superphosphate of Iron. Acid Phosphate of Iron. A mass of soft consistence without inky taste.
The two first salts have often been confounded, being called indifferently Phosphate of Iron.
The Phosphates of Iron are sometimes administered with other phosphates, in the form of syrups. Several new preparations of this kind have been introduced by different pharmaceutists, e. g., Syrup of Phosphate of Iron and Ammonia; Syrup of Phosphate of Iron and Lime; Syrup of Phosphate of Iron and Manganese, &c. The Pyrophosphate of Iron with Soda or Citrate of Ammonia (known generally as Soluble Pyrophosphate of Iron, or simply as Pyrophosphate of Iron) is a scaled preparation, containing a variable proportion of the Pyrophosphate of the Peroxide of iron.*
Med. Prop. and Action. Blood-restoratives, tonics, and alteratives. The Phosphate is best administered in the form of Syrup.
Offic. Prep. of Phosphate of Iron. Syrupus Ferri Phosphatis. (Prepared by precipitating a solution of Granulated Sulphate of Iron, grs. ccxxiv., with a solution of Phosphate of Soda, grs. cc., and of Acetate of soda, grs. lxxiv. The precipitate is collected on a filter, washed, and pressed between folds of bibulous paper; fl. oz. vss. of Dilute Phosphoric Acid are then added; as soon as the precipitate is dissolved, the solution is filtered, and oz. viij. of Sugar added, and dissolved without heat. Dose, fl. drm. j. - fl. drs. ij.
Dose of Phosphate, Perphosphate, Superphosphate, and Pyrophosphate of Iron, gr. iij. - gr. x.
In Cancer, the Phosphates of Iron were highly esteemed by Mr. Carmichael. He administered the following pills: - Ferri Phos. gr. xxx. - ij., Potas. vel Sodae Purge gr. iij., Ext. Aloes gr. iv., Pulv. Glye. j., Alb. Ovi q. 8. ft. pil. xij. Dose, one every two, three, or four hours. At the same time, he applied locally the Phosphate made into a thin paste with water, or an ointment (3ij., Lard j.). As a remedy for Cancer, it is now abandoned.
Venables and Dr. Prout.§ The former directs it to be taken in doses of gr. j. - ij., gradually increased to j. - 3ss. three or four times a day. It appears to exercise a decidedly favourable influence.
The Syrup of the Phosphate of Iron and Lime is a preparation introduced for this purpose. It may be given in doses of fl. drm. j., or more, thrice daily.
* Draper. op. cit.
Essay on the Effects of the Carb. of Iron on Cancer, 2nd Ed., Dub. 1808.
On Diabetes, 8vo, Lond. 1825. § On Stomach and Renal Diseases, p.48.