Guaiaci Lignum et Resina. The Wood and the Resin obtained from the Guaiacum Officinale. Nat. Ord. ZygophyllaAe. Linn Syst. Decandria Monogynia. Source, West Indies and South America. Imported from St. Domingo and Jamaica.

Med. Prop. and Action. Both the Wood and Resin are stimulant, diaphoretic, and alterative. The Wood is best given in decoction (Guaiacum Wood oz. iij., Sassafras and Liquorice-root aa oz. j., Water Ox.) in doses of Oss. - Oj. daily. The Resin, the part most commonly employed, may be given in the form of mixture, but a better form is the Ammoniated Tincture. Guaiacum acts by augmenting the action of the cutaneous capillaries, thereby improving the state of the cuticular function. To obtain its diaphoretic effect, the surface of the body should be kept warm, tepid diluents should be drunk plentifully, care should be taken that the Resin is in a state of minute division, and it should be combined with Opium. If it fail to produce diaphoresis, it acts as a diuretic. In small medicinal doses, gr. x. - gr. xxx. of the Resun, it causes a pleasant sensation of warmth in the stomach, and dryness of the mouth and fauces, and, by proper management, profuse diaphoresis. In larger doses it purges; the heat of the stomach and dryness of the mouth become intense, and, if continued, would produce gastrointestinal inflammation. It appears to have great power in lessening excessive secretion from mucous surfaces.

Offlc. Prep. Of the Wood. Decoctum SarsAe Compositum. (See Sarsaparilla.) Of the Resin. 1. Mistura Guaiaci (Powdered Guaiac Resin oz. ss.; Sugar oz. ss.; Powdered Gum Arabic oz. 1/4; Cinnamon Water Oj.). Dose, fl. oz. j. fl. oz. iss.

2. Pilula Calomelanos Composita

(See Calomelas.)

3. Tinctura Guaiaci Ammoniata (Powdered Guaiac Resin Oz

iv.; Aromatic Spirit of Ammonia Oj. Prepared by maceration). Dose, fl. drm. ss. - fl. drm. j.

Dose of Guaiac Resin, gr. x. - gr. xxx.

It is contra-indicated in all febrile affections, and in inflammatory or irritated states of the gastro-intestinal membrane.

1326. Therapeutic Uses

In Amenorrha, Dr. Dewees* speaks in the highest terms of the Ammoniated Tincture. He states that he gives it with a confidence which he attaches to no other medicine; that he has succeeded with it where almost all other emmenagogues have failed; and that for more than forty years he has almost daily used this medicine in suppressed catanienia, and more especially in cases of long standing, without its having failed in any instance proper for its use. More cannot be said of any remedy. Such strong testimony, from so respectable an authority, demands more attention to the remedy than is usually accorded to it. The cases which Dr. Dewees considers most benefited by it are simple, idiopathic ones, not dependent on organic disease of the uterus or pregnancy. He accounts for the failure of this remedy in the hands of others - 1st, by the system not having been, previous to the use of this remedy, reduced by purging, moderate blood-letting, and low diet, all of which he deems indispensable to its success; and, 2ndly, by the remedy not being properly persevered in. He states that he could furnish a number of instances where it succeeded in restoring the menses, after an interruption varying from nine months to three years. He advises the annexed formula: -1326 Therapeutic Uses 111Pulv. G. Guaiaei iv., Sodas vel Potas. Carb. 3iss., Pulv. Piment. j., Alcohol Dilut. Oj. Let it stand for a few days, and add Spt. Ammon. A. f3j. - f3ij. to every fiv. of the Tincture. Dose, f 3J. thrice daily, gradually increased. If it purge, a few drops of T. Opii may be added; if it constipate, a little Rhubarb may be given. It has proved successful also in the hands of Hannay, Locock, and others.

* Dewees on Diseases of Females, 6th Ed., p. 122-5.