The Common Hop. Nat. Ord. Urticaceae. Linn. Syst. Dioecia Pentandria. Hab. England. Cultivated in other parts of the world.

Med. Prop. and Action. The dried catkins of the female plant (vulgo Hops) are stomachic, tonic, diuretic, and slightly narcotic. Hops contain a volatile oil and a peculiar bitter principle, Lupulite or Humulin. The Volatile Oil contains a Hydrocarbon (C20H16) with valerol (C12H10O2): the latter by the action of Caustic Potash is converted into Valerianic Acid, as shown in the following equation, C12H10O2 + 3 (KO, HO) + 2 HO = 2 (KO, CO2) + (KO, C10H9O3) + H6, and thus the hydrocarbon may be separated from the valerol. (Garrod.) Lupuline is the yellow resinous pulverulent substance separated from the strobiles by rubbing and sifting. Lupuline yields about 11 per cent, of the bitter principle, Lupulite. § The volatile oil is narcotic. The odorous emanations from the oil also possess narcotic properties. Lupuline is tonic, aromatic, and sedative. (See art. Lupuline.)

Offic. Prep. 1. Infusum Lupuli (Hops oz. ss.; Boiling Distilled Water fl. oz. x. Infuse for two hours in a covered vessel, and strain). Dose, fl. oz. j. - fl. oz. ij.

2. Extractum Lupuli (Hop Lb J

; Rectified Spirit Oiss.; Distilled Water Cj. Prepared by macerating the hop in the spirit for seven days, and boiling the residue with the water for one hour, mixing the two extracts, and evaporating at a temperature not exceeding 140°). Lose, gr. v. - gr. xx.

3. Tinctura Lupuli (Hop Oz

iiss.; Proof Spirit Oj. Prepared by maceration and percolation). Dose, fl. drm. ss. - fl. drs. ij.

The Dose of Lupuline is gr. v. - xy. (See art. Lupuline.)

* Bengal Dispensatory, p. 681. Journ. de Pharm., Feb. 1845.

Fsscntials of Mat. Med. and Therap, p. 289. § Garrod, op. cit.

1355. Therapeutic Uses

In Mania and in the Delirium of Fever, a Hop pillow (the Hops having been previously wetted with spirit to prevent rustling) is occasionally employed, with a view of inducing sleep. It is stated to have been successful in the case of George III.; and Pereira * has several times seen it used with success. Their internal use, in the form of Extract, is favourably spoken of by Mr. Mayo. In Delirium Tremens, Prof. G. B. Wood regards the Tincture as an admirable adjunct to Opium, having seen sleep induced by it when Opium alone has failed. In convalescence from this disease, also, he considers it one of our best remedies for sustaining a moderate tonic and soporific influence.

1356. In Dyspepsia, the various preparations of Hops are sometimes given with benefit; perhaps none is superior to a pure bitter ale. In Dyspepsia attended with Pyrosis, the Extract has been found very serviceable.

1357. In Rheumatism, Dr

Maton found the Extract, given internally, very efficacious in allaying pain and in producing sleep. It had a marked effect on the pulse. In the hands of Dr. Bigsby it altogether failed.

1358. In Cancerous And Other Ulcerations, Mr

Freake§; speaks favourably of the external application of powdered Hops, in the form of ointment.

1359. In Painful Swellings And Tumours, Dr

A. T. Thompson|| states that he has seen Hop fomentations afford much relief.

1360. In Intermittent Fevers, Lupuline, In Doses Of Gr

yj. - xij. daily, is occasionally effectual. It is a popular remedy amongst the Neapolitans. ¶ (See art. Lupuline.)