1. Griping and Purging. This may be partially obviated by combining it with a sedative; or it may be necessary, if the stools become bloody and dysenteric, to discontinue it altogether. 2. Sore Throat. Ulceration, or Mortification of the Tonsils, accompanied with fever. In this case, the medicine should be discontinued, and the ulcerated throat treated on general principles. 3. Violent Salivation, which not unfrequently terminates in mortification. 4. A renewal of Salivation at a future period. There are many cases of this on record. In one related by Dr. Christison,* salivation reappeared at the end of four months, although no mercurial had been given in the interval. 5. Eruptions of the Skin, known under the names of Erythema Mercurialis, Eczema Rubrum, Hydrargyria, &c. 6. Erethismus Mercurialis, which is characterised by a great depression of the vital powers, a sense of anxiety about the prsecordia, irregular action of the heart, frequent sighing and faintness, which occasionally proves fatal. The medicine should be immediately discontinued, and the patient exposed to a healthy atmosphere, and tonics and liberal diet employed. 7. Rheumatic Pains and Nodes, resembling those produced by Syphilis. 8. Mercurial Palsy, and other derangements of the nervous system. 9. A cachectic state of the constitution, known as Cachexia Mercurialis.

No certain rules can be laid down respecting the appearance of these ill effects: in some instances, they appear after a few moderate or small doses; in others, it may be continued for months without any apparently ill effects. The appearance of any of them indicates the necessity of immediately relinquishing the use of the remedy. (See also next section.)