Corrosive Sublimate. Chloride of Mercury. HgCl. Hydrargvri Bi-chloridum. Bichloride of Mercury (Pharm. Lond.). Called also the Perchloride, the Hydrochlorate, the Muriate, and the Oxymuriate of Mercury. Comp. Mercury 73.8, Chlorine 26.2, in 100 parts; or 1 Eq. Mercury = 100 + 1 Chlorine 35.5=135.5, Eq. Wt.

Med. Prop. and Action. Alterative in doses of from gr. 1/15 to 1/8. In larger doses it causes much griping and purging; and, in large quantities, it is a powerful irritant poison. The smallest fatal dose is three grains, in the case of a child; the shortest period in which death followed is two hours. When swallowed, it produces corrosion of the stomach; and in whatever way it may obtain entrance into the body, it occasions irritation of that viscus, and of the rectum, inflammation of the lungs, and probably also of the heart, depressed arterial action, oppression of the functions of the brain, and inflammation of the salivary glands. (Christison.) In persons who. have taken large quantities, it has been detected after death in the solids and fluids of the body. It appears to act powerfully upon the urinary organs, as in cases of poisoning by it the urine is extremely scanty in quantity, and after death the urinary organs are generally highly inflamed, whilst the bladder is extremely contracted. It has been said to be more difficult to produce salivation by Corrosive Sublimate than by any other salt of Mercury; indeed, Mr. Clay* states, that in an experience of twenty years, though he has pushed it to a great extent, both in adults and children, he has never been able to produce decided ptyalism by its use. Dr. Holland, however, speaks highly of its efficacy. He states that he has seen its influence in augmenting the secretions, procuring the absorption of morbid growths, altering the state of the skin in many cutaneous disorders, and changing the character of morbid actions generally, in cases where he believes no other medicine, or combination of medicines, would have equal effect. He considers that it is as safe as Calomel. If it cause griping and purging, it should be combined with a small portion of opium. It may be given in the form of pills, or in solution (Liq. Hydrar-gyri Bichloridi, Ph. Lond.) (Corrosive Sublimate, Hydrochlorate of Ammonia aa gr. x., Distilled Water Oj.) in doses of fl. drm. ss. - fl. drm. j. - fl. drs. ij. in some bland fluid. Each fl. oz. j. contains 1/2 gr. of the salt. Externally it is used (gr. 1/2 - ij. ad Aq. fl. oz. j.) as a collyrium or wash.

* Lancet, Aug. 21, 1841.

Medical Notes and Reflections.

Dote of Corrosive Sublimate, gr. 1/20 - 1/8.

It is contra-indicated. - 1, in persons labouring under or strongly predisposed to pulmonary disease, as it occasionally gives rise to great irritation of the lungs; 2, in inflammatory states of the kidneys and urinary organs.

Incompatible*. Alkalies and their Carbonates; all Sulphurets; Acids, excepting Hydrochloric; Soap; Lime Water; Tartar Emetic; Iodides; Nitrate of Silver; Acetate of Lead; all vegetable astringent infusions; Albumen, and all albuminous solutions.