Bed Iodide of Mercury. Hgl. Hydrargyri Iodidum vel Biniodidum. Iodide or Biniodide of Mercury. Called also the Periodide of Mercury. Comp. Mercury 44.25, Iodine 55.75, in 100 parts; or 1 Eq. Mercury = 100 + 1Iodine = 126 = 226, Eq. Wt.

Med. Prop. and Action. Alterative, stimulant, and deobstruent. in doses of gr. 1/16, gradually increased to 1/4, in the form of pill or dissolved in alcohol. In its irritant properties it resembles Corrosive Sublimate. Its effects on the system are similar to those at the Green Iodide, but it is much more irritant in its action. In long-continued doses it produces salivation. It requires to be given with great caution, and to be discontinued if it cause much irritation. Left in contact with the skin, it causes inflammation; and when applied in the form of ointment to ulcerated surfaces, it occasions great pain and irritation.

Offic. Prep. Unguentum Hydrargyri lodidi Rubri (Red Iodide of Mercury gi. xvj.; Simple Ointment oz. j ). This ointment contains one-fourth as much of the Red Iodide as the Ung. Hyd. Iod. Rub. of the Pharm. Dub.

Dose of the Iodide, gr. 1/20 - 1/4.

1466. Therapeutic Uses

In Secondary and Constitutional Syphilis, Dr. Octavius Boyle* considers this the best form of Mercury which can be used. He advises it in doses of gr. 1/2, twice daily, in the Extract of Gentian, and administers at the same time fj. of Mist. Guaiaci. He continues this till a decided impression is produced, and the gums become slightly sore. In Syphilitic Eruptions of the Skin, a weak ointment of this salt (gr. viij. - xij., Adipis oz. j.) is very efficacious; but the pain which it sometimes occasions is an objection to its use. In Acne Syphilitica it is highly spoken of by Dr. Todd; a cold douche vapour-bath being used at the same time.

1467. In Bronchocele, The Bed Iodide Is One Of The Best Applications We Possess

The great success which attended its use in India by Capt. Cunningham, of the 12th Cavalry, first attracted attention to it; and the evidence adduced by Dr. F. Mouat established its claims beyond a doubt. It has since been used both in India and in Europe with great success. The strength originally proposed (3ix. ad Ung. lb. iij.) has, however, been found far too powerful for ordinary use. It was directed to be rubbed in for ten minutes in the morning, and the patient to be exposed to the sun's rays as long as they could be endured. Dr. Frodsham* tried to substitute artificial heat for the sun's rays, but found it ineffectual. In Elephantiasis Arabum it is favourably spoken of by Mr. F. Day, of Cochin: he found the ointment {ante) far too strong, and substituted a weaker one (gr. j. ad Ung. 3V.): even this causes at first slight irritative fever and augmentation of the size of the limb, but as these subside improvement soon becomes manifest. The strength of the ointment may be gradually increased. My own trials with Mr. Day's ointment in Elephantiasis have been most satisfactory.

* Med. Times, vol. xviii. p. 169. Cyc. Pract. Med., vol. i. p. 23.

\ Indian. Ann. of Med. Sci, 1857, vol. iv. p. 436.

1468. In Other Cutaneous Diseases, It Also Occasionally Proves Useful

Dr. Neligan found great benefit from it in Pityriasis. Rayer§ speaks highly of it in inveterate Psoriasis; and in a case of Carcinomatous Ulcer of the Face, Dr. Brescht || effected a cure by an ointment composed of 1 part of the salt to 7 of lard. In Lupus the Red Iodide is favourably spoken of as a local application by Mr. M'Whinnie.¶ The following is the formula he recommends: -1468 In Other Cutaneous Diseases It Also Occasiona 132 Hyd. Biniod. 3j., Adipis 3ij., Emp. Opii 3vj. The consequent swelling and pain are to be relieved by emollient poultices.

1469. In Chronic Glandular Enlargements and other Tumours probably of Strumous origin, the ointment of the Red Iodide has been found of striking benefit by Dr. M. T. Sadler,** and others. Dr. Sadler has also found it useful in promoting the removal of gouty deposits in the neighbourhood of joints.

1470. In Epilepsy, Dr

Fuller found the Red Iodide most serviceable, especially in cases where there was reason to suppose that the disease depended upon thickening of the dura mater. His formula is an extemporary one, formed by dissolving Potass. Iod. gr. v. - x. in Liq. Hydrargyri Bichloridi (Pharm. Lond.) f3j. - f3ij. Given thus in solution, it becomes readily absorbed, and speedily produces its specific effects. The exact dose of the above solution is not stated.

1471. In obstinate cases of Ophthalmia Tarsi, and in Opacity of the Cornea, a thin ointment (gr. ij., Cerate ij., Oil j.) is stated by Pereira to have been successfully employed. It should not be used until other remedies have failed.