Iodoformum. Sesqui-iodide of Carbon, Yellow Iodide, or Ter-iodide of Formyle. Formed by the mixture of concentrated alcoholic solutions of Iodine and Potassa. Introduced into practice in 1848 by Dr. Glover.§ It occurs in the form of small pearly crystals of the colour and odour of saffron, and of a sweet taste. It is volatile, soft to the touch, insoluble in water, soluble in alcohol, and in ether. Chem. Form. C2HI3.
Med. Prop. and Action. In small medicinal doses Iodoform, according to Dr. Glover, appears to possess a union of tonic, stimulant, and alterative properties, exercising, at the same time, a remarkable influence on the nervous system. Though ordinarily unirritating, it may, in Large doses, prove fatal; 50 grains, in Dr. Cogswell's || experiments, having destroyed a strong dog. The odour of the Iodine was detected in the blood, brain, and muscles. The dose is gr. j. - iij. twice daily, in the form of pill. Externally, it may be applied in the form of ointment (gr. xxx. - gr. lx. ad Ung. oz. j.). As an anAesthetic, it has been supposed to exercise effects similar to Chloroform, but the experiments of Righini and of Bouchardat* show that though its influence on leeches, fishes. &c, is very marked, yet that on Mammalia it will bear no comparison to Chloroform, except, indeed, in its local operation. Introduced in the form of suppository into the rectum, M. Moretin found its local anAeesthetic influence was so marked that defecation could be accomplished without consciousness on the part of the patient; and this was further shown by the anodyne influence it exercises when applied to cancerous and other ulcers. As a disinfectant, its powers have been asserted by M. Righin.
* Mem. del Med. Contemp., 1842. Brit, and For. Med. Rev., vol. ii. p. 244. Grafe and Walther's Journ., vol xxi part i.
§ On the Physiolog. and Med. Prop, of Iodoform, Edin. 1848.
|| Essay on Iodine, p. 122.