Ipecacuanhv Radix. Ipecacuan. The root of Cephaelis Ipecacuanha. Nat. Ord. Cinchonaceae. Linn. Syst. Pentandria Monogynia. Source, the Brazils and Mexico.
Med. Prop. and Action. Emetic, in doses of gr. xx. - gr. xxx. of the powdered root; expectorant and diaphoretic, gr, j. - gr. ij.; alterative, gr. 1/4 - 1/2. Active principle, Emetina(see that article). It possesses considerable sedative powers, as is shown by its influence in hAemorrhagic diseases. As an emetic, it is mild, safe, and certain; it does not operate so rapidly as some other emetics, and does not leave that amount of depression and weakness which follows the use of Tartar Emetic. It is to be preferred, when the powers of the stomach require to be maintained, and when vomiting is requisite in delicate subjects, and in children; for the latter, the Vinum IpecacuanhAe, in doses of exx. - fl. drm. 3., till it cause vomiting, is the best formula. Some persons, from idiosyncrasy, are unable to take Ipecacuanha; in such, even the smell of the powdered root produces a distressing sense of suffocation.¶ The powder should be kept in closely-stoppered bottles, and exposed to the light. Boiling renders it inert; it should not, therefore, be given in decoction. Infusion of Nut Galls is the best antidote for an over-dose. Its external application is highly spoken of by Dr. Turnbull,* who considers it far superior to Tartar Emetic as a counter-irritant. He advises 3ij. of the powder (or Emetine gr. xv.) to be incorporated with 3ij. of Olive Oil and 3iv. of Lard. This, rubbed on the skin for a few minutes, once or twice a day, produces a copious crop of small pustules, unattended with pain, which remain out for many days and leave no scars. In this last point it has an advantage over Tartar Emetic ointment, for which Dr. Turnbull proposes it as a substitute. Dr. Graves states that he often gives the infusion of Ipecacuanha in the form of enema: and that, employed in this manner, it is a remedy of very considerable value, and not sufficiently appreciated by most modern practitioners. When applied locally in the form of poultice or paste to venomous bites or stings, it often allays in a remarkable manner the pain and irritation, and, in such cases, is regarded by some as almost a specific.
* Gaz. des Hopitaux, Sept. 7,1843.
Ranking's Abstract, 1859, vol. xxix. p. 83.
Brit, and For. Med. Rev., July 1, 1843.
§ Journ. des Conn. Med Chir., March 1843.
|| See Med. Gaz., Nov. 15, 1850.
¶See a case related by Dr. Watson, Lectures, vol. ii. p. 52.
Offic. Prep. 1. Pulvis Ipecacuanha cum Opio. (See art. Pulvis IpecacuanhAe cum Opio.)
xx.; Powdered Ipecacuan grs. lx.; Tincture of Tolu fl. oz. ss.; Refined Sugar oz. xxiv.; Powdered Gum Arabic oz. j. j Mucilage of Gum Arabic fl. oz. ij. or q. s.; Boiling Distilled Water fl. oz. ss. To be divided into 720 lozenges;. Each lozenge contains gr. 1/36 of Hydrochlorate of Morphia, and gr. 1/12 of Ipecacuan.
a. Vinum Ipecacuanhas (Ipecacuan bruised oz. j.; Sherry Oj. Prepared by maceration). Dose, as an emetic, fl. drs. iij. - fl. drs. vj. As an expectorant, ev. - fl. drm. ss.
Dose of Ipecacuanha: as an emetic, gr. xx. or more; as an expectorant and diaphoretic, gr. 1/2 - gr. ij.