Carbonate of Lithia. LO, CO2. A compound of 1 Eq. Lithia = 7 + 1 Carbonic Acid = 22 = 29, Eq. Wt.
Med. Prop. and Action. Alkaline, diuretic, and lithontriptic. The value of Lithia depends on its affinity for Uric Acid, on its small combining proportion, and on the great solubility of Urate of Lithia. The Carbonate of Lithia renders the urine more alkaline than the corresponding salts of soda and potash (Garrod*).
Dose, gr. iij. - gr. vj. It may be given in aerated water; free dilution aids its diuretic action (Garrod).
As a solvent of Uric Acid Calculus, it was first proposed by Mr. Ure,t in 1843; and the success he met with in dissolving extracted calculi warrants the belief that it is the most efficacious solvent yet known. He found that one grain of Lithia dissolved in fj. of Aq. Dest. took up at 98° F. 2.3 grains of Uric Acid; and that a solution of 4 grains in fj. of water, at the same temperature, lessened the weight of a calculus composed of Uric Acid with alternate layers of Oxalate of Lime, 5 grains in five hours. ''If," Mr. Ure adds, " by means of injections we can reduce a stone at the rate of a grain an hour, as the above experiment would lead us to anticipate, we shall not merely diminish its positive bulk, but further loosen its cohesion, disintegrate it, so to speak, causing it to crumble down and be washed away in the stream of the urine." Its solvent powers are reported highly of by Binswanger and other German authorities. Dr. Garrod has recently called attention to the value of the salts of Lithia in cases of Uric Acid Diathesis connected with Gravel, and in cases of Chronic Gout. This recommendation is based upon the fact that Lithia possesses great affinity for Uric Acid, and that the Urate of Lithia is the most soluble of all the urates. Hence the value of the Lithia springs of Baden-Baden, as shown by Dr. Althaus.* Lithium has also been lately discovered in the Bath thermal waters by Prof. Roscoe.
* Essentials of Mat. Med. and Therap., pp. 93, 94. Pharmaceut. Journal, vol. iii.
Braithwaite's Retrospect, xli. p. 29.
1734. LithlAe: Citras. Citrate of Lithia. 3 LO, C12H5O11. Prep. Made by dissolving 50 grs. of Carbonate of Lithia in 1 fl. oz. of Water containing 90 grs. of Citric Acid, by the aid of heat; evaporating the solution, and drying the residue at a temperature of 240°.
Med. Prop. and Action. The same as those of Carbonate of Lithia. Dose, gr. v. - gr. x.