Musk. A peculiar secretion found in the prae-putial follicles of Moschus Moschiferus, the Musk Deer, an animal belonging to the order Ruminantia, of Cuvier. It is an inhabitant of the mountains of Thibet, and other parts of Central and Northern Asia. The dried inspissated secretion (Musk) is imported from China.

* Lancet, Sept. 13, 1851. Ibid.

Lancet, May 3, 1851.

Med. Prop. and Action. Stimulant and anti-spasmodic in doses of gr. vj. - gr. lx., repeated every six or eight hours. It may be given in the form of bolus, emulsion, or Tincture (gr. cxx. ad. Spt. Rect .oj.). In large doses it is narcotic, and by Eastern nations is regarded as an aphrodisiac. Taken internally, it causes a sensation of warmth in the stomach, which gradually extends over the whole body: it increases the action of the heart and arterial system, and augments the secretion of urine and perspiration, to both of which it communicates its odorous principle. This has also been detected in the blood, and after death in the solids of the body. Cullen legarded it as the most powerful anti-spasmodic in the Materia Medica, and, when obtained pure, it is doubtless a remedy of great efficacy; but its high price causes it to be so extensively adulterated, thau as it is met with in commerce, it can rarely be employed with the certainty of obtaining a proper and uniform effect.

Dose, gr. v. - gr. lx.

Incompatibles with a watery infusion. Corrosive Sublimate, Sulphate of Iron, Nitrates of Silver and Mercury, some other acidulous salts, and Infusion of Cinchona.

1835. Therapeutic Uses

Spasmodic Diseases. In purely Spasmodic or Nervous Asthma, Musk is often productive of benefit. The average dose is from 10 to 15 grains, but this must be regulated by the severity of the attack. Dr. Ahrensen* states that. he applied Musk endermically in this disease with decided benefit. From gr. vj. to xv. were used at each application.

1836. In Epilepsy, Musk Is Occasionally Beneficial

Dr. A. T. Thompson states that he can bear testimony to its powerful influence in diminishing the violence of the paroxysms of idiopathic Epilepsy, and in greatly lengthening the intervals, when the dose is carried to the extent of 5j. every eight hours. He prefers giving it in the form of a bolus.

1837. In Chorea, it has been used occasionally with benefit, but it most frequently fails in producing any good effects. Cases successfully treated with it are recorded by Dr. Powell.

1838. In Hooping- Cough, Musk has been long and successfully employed by the Russian physicians. Sir George Lefevre§ states that, after the febrile stage has subsided, it seems to exercise a specific influence; he adds, "A grain of Musk, three or four times a day, will in general arrest the most convulsive species of coughing in a few days."

* Essay on the Endermic Method, Cyc. Pract. Med., vol i. p. 102.

Med. Trans., vol. v.

§ An Apology for the Nerves, p. 178.

1839. In Tetanus, Musk has been employed with reputed benefit by Founder, Pescay,* and others; but it failed in the hands of Sir J. Macgrigor; and Mr. S. Cooper states that 150 grains were given to a girl thirteen years old, affected with incipient Tetanus, with no salutary effect.

1840. In Infantile Convulsions occurring during dentition, where great irritability of the brain exists without plethora, and where the exciting cause, if possible, has been removed, and the convulsions still continue, anti-spasmodics are indicated; and Musk (gr. ij. - v.), in the form of enema, often proves of the highest service. Assaftida is a good substitute. In Puerperal Convulsions, Mr. Michell§ strongly advocates Musk, given in doses of from j. - ij.