Nitro-muriatic Acid. Aci-dum Nitro-hydrochloricum, seu Nitro-muriaticum. Aqua Regia. A mixture of one part of Nitric Acid and two parts of Hydrochloric Acid. It is distinguished from all other acids by its property of dissolving gold.

Dilute Nitro-Hydrochloric Acid. Acidum Nitro-Hydrochloricum Dilutum. Prepared by mixing 2 fl. oz. of Nitric Acid with 26 fl. oz. of Distilled Water and adding 4 fl. oz. of Hydrochloric Acid. Sp. Gr. 1.074.

Med. Prop. and Action. The strong acid is caustic and escharotic. The dilute acid, in doses of ev. - xv., properly diluted, is given internally as an alterative and tonic. Externally it is used largely diluted as a bath or stimulating wash. (See Chronic Hepatitis, infra.) As it is prejudicial to the teeth, the mouth should be washed out with an alkaline solution, after each dose of the medicine.

Dose of Acidum Nitro-Hydrochloricum Dilutum, ev. - exv.

1911. Therapeutic Uses

Calculous Diseases. In the Oxalic Acid Diathesis, Dr. Prout advises the mineral acids generally, either alone or combined with the Sulphate of Iron or Quinine. He particularly recommends the Nitro-muriatic Acid in Distilled Water, till the Lithate of Ammonia or Lithic Acid begin to appear in the urine, or for a stated period of three or four weeks. By adopting such a course of acids three or four times in the year, and by a carefully regulated diet, he states that he has seen the diathesis gradually subdued, and at length removed altogether. In all instances its effects should be watched; and when the Lithates or Lithic Acid begin to appear, its use should be discontinued. It, in common with the other acids, should be left off after a time; as, when too long persisted in, it not only ceases to do good, but in most instances does harm. The above treatment, which is supported also by the experience of Dr. Golding Bird, should be combined with an animal diet, avoiding all food containing starch, sugar, &c. In the Cystic Oxide Diathesis, Dr. Prout has seen most benefit from the Nitro-muriatic Acid. Under its use, he states that he has seen the peculiar smell of the urine which accompanies this diathesis very much abated; and all the properties of the secretion so much improved that the peculiar principle itself has for a time disappeared. The complaint, however, has generally shown a disposition to return when the medicine has been left off; but by recurring to the acid, the deposition has been again suspended.

1912. In Chronic Hepatitis, and in Acute Hepatitis when the acute symptoms have been subdued by depletion and other antiphlogistic measures, Nitro-muriatic Acid, both internally and externally, has been used with great advantage. It was first proposed by Dr. Scott, in 1796. Mr. Annesley, who employed it extensively, placed great reliance on it; and Sir J. M'Grigor observes, after employing it in about 200 cases, "One fact we are clear and decided in, that the injury to the constitution is infinitely less from the acid than from the mercurial ointment, and that men are not half the time convalescent from the first as they are from the last remedy." It is in the form of bath that it is most used and proves most serviceable. Sir Ranald Martin* gives the following directions for its use: - 1. The proportions of acid are, Hydrochloric Acid fiy., Nitric Acid fij., Water f v. 2. Two gallons of water (about ten bottles) may suffice for a bath. 3. To each gallon of water add f iij. of the above acid. 4. The bath thus prepared will keep in use for three days, by adding f ss. of the acid and Oj. of water, morning and evening, in order to make up for the waste by evaporation. 5. A portion only of the bath to be heated for use, after which it is to be added to the remainder, so as to make the whole of a comfortable warmth. 6. Let both feet be placed in the bath, while the inside of the legs and thighs, the right side (over the liver), and inside of both arms, are sponged alternately. This should be continued for ten or fifteen minutes morning and evening. 7. While using the bath, a gentle aperient should be taken every other morning. 8. Earthenware or wooden vessels should be preferred as foot-baths, and all the sponges and towels should be kept in cold water, as the acid corrodes them. 9. In urgent cases, a general bath to envelope the whole body may be used. 10. If the acid-bath create much irritation of the skin, the quantity of the acid may be diminished. 11. The influence of the acid is not in the least degree counteracted by Opium, even when exhibited in the largest doses.

* Op. cit., p. 847.

On Stomach and Renal Diseases,

4th Ed., p. 73. Op. cit., p. 234.

1913. In Jaundice, the acid, as advised in the preceding section, was praised by Annesley, Scott, and others. Dr. Copland states that he has found it decidedly beneficial in some cases, when employed internally as well as externally. It is inadmissible when inflammatory action is present. In Dysentery, especially when connected with hepatic disease, Mr. Annesley directs lotions of this acid (ut supra) to be applied to the abdomen. In Dropsy from disease of the Liver or Spleen, much service will accrue from the Nitro-muriatic Acid bath, or from sponging the surface of the hypochondria, night and morning, with a warm lotion containing these acids, or from the internal use of them. (Copland.)

* Johnson and Martin on Tropical Climates, &c, p. 286; also, Prov. Joum., Sept. 1850.

Dict. Pract. Med., vol. ii. p. 310. Ibid., vol. i. p. 610.

1914. In Chronic Bronchitis, sponging the surface of the chest with the acid lotion (sect. 1912) is often of great service in checking profuse expectoration, and in otherwise mitigating the severity of the symptoms. Dr. Graves* was in the habit of prescribing in this disease a liniment made by diligently mixing f3j. of the Nitro-muriatic Acid and j. of Lard, by means of a wooden or ivory spatula. When this mixture is complete, f 3ij. of the oil of turpentine is added.

1915. In Acne Rosacea, much benefit often results from the application of a lotion containing this acid; and also from the use of the acid foot-bath (sect. 1912). It is favourably spoken of by Biett, Cazenave, Schedel, Copland, &c. In Favus, Mr. E. Wilson advises its internal administration.

1916. In Scarlatina, an excellent gargle is formed by diluting this acid with water, and sweetening with honey. It should be made of such a strength as to cause slight smarting, without actual pain. It may also be advantageously given internally, in doses of gutt. j. - ij. of the strong acid, in decoction of Cinchona, five or six times daily.