Krameria. The dried root of Krameria Tri-andra. Nat. Ord. Polygalaceae. Linn. Syst. Tetrandria Monogynia. Source, Peru.

Med. Prop. and Action. Astringent. It is best administered in infusion, or in the form of extract. Its astringency depends upon the presence of Tannin, of which the good root contains about 40 per cent. It contains also a peculiar acid (Krameric Acid) and a red astringent matter.* It is a powerful and valuable astringent.

Offic. Prep. 1. Extractum KrameriAe (Rhatany in coarse powder lb. j.; Distilled Water Cj. Prepared by maceration, percolation, and evaporation). Dose, gr. iij - gr. xx.

2. Infusum Krameriae (Rhatany Bruised Oz

ss.; Boiling Distilled Water fl. oz. x. Infuse one hour, and strain). Dose, fl. oz. j. - fl. oz. ij.

3. Pulvis Catechu Compositus

(See Catechu.)

4. Tinctura Krameriae (Rhatany Bruised Oz

iiss.; Proof Spirit Oj. Prepared by maceration and percolation). Dose, exxx. - fl. drs. iss.

Dose of Rhatany in powder, gr. x. - gr. xl., or more.

Incompatible!. The Mineral Acids; Lime Water; solutions of the Salts of Iron, of the Acetate of Lead and Iodine; all solutions containing Gelatine.

Contra-indications. 1, Inflammatory states of the alimentary canal; 2, obstinate constipation.

* Garrod, Ess. Mat. Med. and Therap., p. 166.

2354. Therapeutic Uses

In Atonic or Passive Hemorrhages, Rhatany, either in the form of infusion or extract (ut supra), has been found signally beneficial. It is doubtful whether it possesses any advantages over Tannin, excepting in general being more easily obtainable In HAematuria, it was found by Dr. "Watson* to be effectual, after all ordinary measures had failed. He gave it in doses of Aej. of the extract, thrice daily. Sir B. Brodie also found it efficacious. In passive Hemorrhage from the Intestines, it was successfully employed by Lombard, of Geneva; and M. Rilliet relates two cases of intestinal HAemorrhage in new-born infants, which were cured by injections of the infusion of Rhatany, and compresses soaked in the same, applied to the abdomen. In Menorrhagia, particularly when occurring about the usual time of the cessation of the menses, Dr. Dewees§ speaks highly of the efficacy of Rhatany, and quotes the successful employment of it by Gardien and Ruitz. He employs the annexed formula: -2354 Therapeutic Uses 199 Ext. Rhatan. 3ij., Pulv. Rhei 5ss., Syrup q. s. ft. pil. xl., sumat. ij. ter in die. He adds that, although he found this quantity generally successful, he should not hesitate to increase it greatly, if it were necessary.

2355. In Leucorrha, attended by relaxation of the tissues generally, and by debility, the Extract, in doses of gr. xx. daily, proves serviceable in arresting the discharge, and giving a healthy tone to the system. The infusion may, at the same time, be used as an astringent injection.

2356. In Ozena, Dr

Detmold,|| of Hanover, advises the following formula: -2356 In Ozena Dr 200 Decoct. Rhataniae fxij., Calcis Chlor. 3j. - 3ij., M. Of this, fss. is to be injected into the nostrils, three or four times daily, with a syringe, whose point is sufficiently long to carry the fluid up into the nasal passages. Under its use, the most fetid and profuse nasal discharges were benefited or cured.

2357. In Chronic Catarrhal Ophthalmia, Dr

M. Pavise recommends a strong infusion of Rhatany as a collyrium. It may be applied three or four times a day, with or without a few drops of Liq. Plumbi He found it an efficacious remedy.

2358. In Chronic Diarrhoea, It Has Been Successfully Employed By Dr

Hurtado,¶ and other Spanish physicians. It appears to be chiefly useful when the stools are mucous and slimy, and in the absence of all inflammatory action.

2359. In Intermittents, a strong decoction has been highly spoken of as an anti-periodic, but its efficacy is doubtful.

* Lectures, vol. ii. p. 668.

Loc cit

Gaz. Medicale, Dec. 30, 1848.

§ On Diseases of Females, p. 156,

|| Brit. For. Med. Rev., No. xxiv.

¶ Joum. de Med , t. xxxvii. p. 216.