In Inflammatory, Continued, and Remittent Fevers, Tartar Emetic is a most valuable remedy, fulfilling two important indications, viz. subduing the morbidly increased action of the heart and arterial system, and determining freely to the skin. Unless contra-indicated by great gastric irritability or cerebral complications, an antimonial emetic, at the outset of the attack, may be given with manifest benefit, although it does not, as formerly supposed, " cut short" the fever. In the more advanced stages of fever, Tartar Emetic, in doses of from gr. 1/8 to 1/4, every one or two hours, either alone, or in combination with salines, or with Opium, exercises a most beneficial influence. In those cases where, either from great irritability of the stomach or from the delirious state of the patient, it is inadvisable or impossible to administer Antimony by mouth, Prof. Graves* advises its exhibition by means of an enema. For this purpose, gr. ij. - iij. in fiv. - fvj. of mucilage, should be thrown up high into the bowels, by means of a long flexible tube. In this way, he observes, you can secure all the good effects of Antimony in overcoming congestion of the brain, and in procuring sleep. In the cerebral complications of fever, he speaks in the highest terms of the efficacy of a combination of Tartar Emetic and Opium; a very valuable formula, which is often borne and is productive of benefit, when either medicine, used singly, either fails or is inadmissible. In the third and last stage, he also has employed it with evident benefit conjoining it with stimulants, thus: -246 Therapeutic Uses Fevers 27 Mucilag. AcaciAe

fss., Syr. Papav. Alb. fj. (vel T. Opii xx.), Ant. Tart. gr. ij., Camphor. gr. xv., Moschi ij., Aq. fivss., M. Dose, one table-spoonful every two hours. About half a grain of Tartar Emetic, and ten drops of Tincture of Opium, should enter into each draught, and should be repeated every two hours, until copious discharges of yellow faecal matter take place, when the patient is greatly relieved, and generally falls into a profound sleep. His testimony in favour of this remedy is very strong.

* Clinical Lectures, vol. i. pp. 167, 184, 197, et seq.

247. In Intermittent Fevers, an antimonial emetic, unless contra-indicated by great gastric irritability, given at the outset of the attack, is attended with evident benefit. In mild cases, a complete cure is often effected by the continued use of Tartar Emetic, in doses of from gr. 1/8 to 1/6, every two hours; strict attention being, at the same time, paid to the state of the bowels. A practice similar to this is advocated by Dr. Moore,* of the Gwalior Contingent Force, in the intermittents of Upper India. After a brisk purgative, it having been ascertained that the fever is not complicated with any local affection of important viscera or organs, the antimonial treatment is commenced. Dr. Moore employs four mixtures, named A, B, C, and D, of which the dose is fj., every hour or half-hour. A contains one grain of Tartar Emetic in fc. of water; B, one grain in fl.; C, one grain in fxx.; and D, one grain in fx. The chief object in view is not to purge or cause vomiting, but simply to prostrate the patient's strength so completely, that when the first stage of fever has commenced, it must work on the patient's strength, already debilitated by the nauseating doses of Tartar Emetic. In like manner, the prostration of the strength is kept up during the second and third stages of the fever. The mixture D is commonly used for adults; fj. of the solution (1/10 of a grain of the salt) repeated every hour. For women and children, the weaker forms may be used. Should complication exist, they should be met with the usual remedies, but they need not interfere with the continued use of Antimony. Dr. Moore, who has extensively tested this treatment, states that it is attended with unequivocal success. It is well worthy of a further trial.