The bark of the root of Simaruba Amara. Mountain Damson. Nat. Ord. Simarubaceae. Linn. Syst. Decandria Monogynia. Source, Guiana and Jamaica.

Med. Prop. and Action. Tonic and astringent, in doses of gr. xx. - gr. xxx. of the powder; or ft. oz. j. - fl. oz. ij. of the infusion (gr. clxxx. - Aq. Ferv. Oj.). In larger doses it is emetic. It is advantageously combined with carminatives or opiates. It is a mild and efficacious bitter tonic, but has no advantage over other remedies of the same class. Active principle, Quassine.

Dose, gr. xv. - gr. xxx.

Incompatibles. The Carbonates of Alkalies; Lime-water; the Salts of Lead, Silver, and Mercury.

Therapeutic Uses. Similar to those of Quassia.

2502. In the advanced stages of Diarrhoea and Dysentery, it is stated to be very efficacious. Whilst inflammation continues, it is not admissible; but when the fever has abated, if the tenesmus continue, with a weak and sinking state of the pulse, it allays this symptom, and also griping; it promotes the secretion of urine, determines to the surface, and restores the tone of the intestines. (A. T. Thompson. §) In Dysentery, it is highly spoken of by Dr. O'Brien || and others.

* Trans. of Lond. Ph., 1851, p. 321. Lectures, vol. ii. p. 838. % Diseases of the Skin, p. 158.

§ Dispensatory, p. 731. || Trans. of Irish Col. of Physicians, vol. v. p. 221.