Borax. SodAe Biboras. Biborate of Soda. NaO, 2 BO3 + 10 HO. Called also the Borate or Sub-borate of Soda. Comp. Soda 16.23, Boracic Acid 36.65, Water 47.12, in 100 parts; or 1 Eq. Soda = 31, + 2 Boracic Acid = 70, + 10 Water = 90 = 191, Eq. Wt.

Med. Prop. and Action. Refrigerant, diuretic, and emmenagogue. It has also been employed as a solvent for calculi. Dr. Binswanger,* who has examined the properties of this salt, draws the following conclusions: - 1. Its action is very similar to that of the Carbonate of Soda; like it, it has an alkaline reaction, it acts as an antacid, and, when in solution, it absorbs carbonic acid, and dissolves fibrine, albumen, caseine, and uric acid. Swallowed in large doses, it occasions oppression of the stomach, nausea, and vomiting. It becomes absorbed into the system, and is afterwards eliminated by the kidneys, and other secreting organs. It was detected in the blood of the portal vein, in the bile, and in the saliva, and has, therefore, probably, an influence on the process of chymification. If taken in large and repeated doses, it produces the same injurious effects as the other alkalies - deranged digestion, a scorbutic condition of the body, and sometimes an impetiginous eruption. 2. It has no specific power of exciting uterine contractions, of promoting menstruation, or of curing aphthous ulceration; though, like the carbonated alkalies, it may, by relaxing muscular fibre, slightly relieve spasm of the uterus; or, by its liquefacient properties, promote evacuation of the menstrual fluid; or, by its mild alkaline qualities, improve the condition of the skin and mucous surfaces. Its power as a solvent of calculus is very great. Externally applied, it is a mild and efficient detergent.

Offic. Prep. Mel Boracis (finely powdered Borax grs. lxiv.; Clarified Honey oz. j. Mix). Used as an application to aphthous conditions of the tongue and throat.

Dose of Borax, gr. xx. - lx.

Incompatibles. Most Acids; Potash; Ammonia; the Sulphates, Muriates, and Phosphates of earths; the Chlorides of Magnesia and Lime.

2527. Therapeutic Uses

In Aphtha and Aphthous Ulceration of the Mouth, the Mel Boracis is a popular and efficient application. Dr. Watson advises equal parts of this linctus, incorporated with Syrup of Poppies, as a good form, antacids being given internally at the same time. In the Aphthous Ulceration which attends the advanced stages of Phthisis, he states that he has employed it with advantage. In Cracked Tongue, Dr. Brinton found the following formula peculiarly serviceable: -

2527 Therapeutic Uses 207 SodAe Bibor. ij., Glycerini fj., Aq. fiv., M. ft. applicatio.

2528. In Uterine Affections, Borax has long been esteemed by the German physicians; but it was not employed in British practice until it was introduced a few years since by Dr. Copland, § who appears to place much dependence upon its efficacy. Dr. Rigby|| observes that it seems to possess a peculiar power in exciting the activity of the uterus, and that he has employed the following formula in tedious Labours, where there is deficiency of Uterine contractions, with the best effect: -2527 Therapeutic Uses 208 ErgotAe j. - ij.,

* Prize Essay, 1848, quoted by Pereira, vol. i. p. 572. Lectures, vol. i. p. 802.

Dublin Med. Press, April 22,1S57. § Dict. Pract. Med., various articles. || System of Midwifery, p. 209.

SodAe Bibor. gr. x., Aq. Cinnam. fiss., M. ft. haust. Dr. Tyler Smith* speaks of it as a remedy of minor power in controlling Uterine HAemorrhage. He considers that it is absorbed into the blood, and that through this channel it acts upon the spinal cord and the nerves of the uterus. In Chlorosis, Dr. Copland advises the following formula: -2527 Therapeutic Uses 209 SodAe Biboratis ij., Sulphur. PrAecip. 3j., Mucilag. Arab. q. s. ft. pil. xxiv., cap. iij. ter quo-tidie. In Amenorrha, he prefers the subjoined pills: -Sodas Bibor. 3ss., Aloes Socot., Pulv. Capsici āā j., Ol. Lavand. q. s. ft. pil. xviij., cap. ij. ter quotidie. In Dysmenorrha, it has also been given with advantage, combined with Ext. BelladonnAe. In Puerperal Diarrhoea, if the lochia be suppressed, and in Puerperal Convulsions, if the os uteri be rigid and undilated, Dr. Copland advises the Biborate, in doses of j. - 3ss. It may, in these cases, prove a useful adjunct to other measures, but it should not be trusted to alone.