The late Dr. Bedingfield* states that he treated forty cases of Chorea with the Oxide of Zinc, and in one only did it fail to effect a cure. He advises to commence with gr. v., which dose may be gradually increased, until an impression is made upon the disease. Dr. Crawford, also, found it uniformly successful. He observes, that it is much more manageable than the Sulphate; and that he has increased the dose to gr. xxv., without producing any injurious effect. Dr. Copland advises the addition of Cupri Ammoniat. (gr. ij.) to each dose of the Oxide, stating that it prevents the remedy from irritating the stomach. In Epilepsy, its use was first warmly advocated by Dr. Herpin, but he appears to have subsequently changed his opinion, substituting for it the Ammonio-Sulphate of Copper. Dr. Radcliffe § found no benefit from it whatever in nine cases treated on Dr. Herpin's plan.

2843. In The Convulsions Of Children, The Oxide Of Zinc Is Strongly Recommended By M

Guersant.|| One grain may be given at the commencement, and the dose gradually increased to gr. xx. daily. It is best given in powder, with a little sugar.

2844. In Hooping-Cough, M

Guersant recommends the Oxide, in doses of gr. j. - iij. (according to the age of the child), in combination with equal parts of the extract of Hemlock or Belladonna. Loeffer, also, speaks highly of its efficacy when used externally with oil, in the form of liniment, as well as internally. Hochsteker ¶ regards it as a specific.

2845. In The Intermittent Fevers Which Occur In Barbadoes, Dr

Hendy found the Oxide, in doses of gr. ij. - v., effectual, even when Bark and other remedies had previously failed. Sir Gilbert Blane* bears similar testimony to its value.

* Compendium of Med. Practice, p. 51. Cyc. Pract. Med., vol. i. p. 411. Du Prognost., &c., d'Epilepsie, Paris, 1852. § On Epilepsy, Lond. 1858. || Med. Times, vol. xvi. p. 575. ¶ Ann. de Therap., 1860, p. 252.

2846. Chronic Dysentery, which resists all other remedies, occasionally yields to a persevering use of the Oxide, in doses of gr. iij. - v., thrice daily.

2847. In Chronic Alcoholic Intoxication, The Oxide, According To Dr

Marcet. is the proper remedy for the nervous symptoms which so often exist. It is necessary for the patient to abandon drinking his usual stimulants, and to take Zinci Oxid. gr. ij. twice daily, in the form of powder, an hour after each meal. The dose may be increased in the ratio of gr. ij. every third day, until the patient takes gr. vj. - viij. twice daily. This course, persevered in for periods varying from three to six weeks, proved, in Dr. Marcet's cases, signally beneficial. It is well worthy of a further trial.

2848. In purulent Ophthalmia, Scrofulous Ophthalmia, and in Ophthalmia Tarsi, the following formula, long known as " the Ophthalmic Ointment of Janin," has been found serviceable: -

2847 In Chronic Alcoholic Intoxication The Oxide A 250 Zinci Oxid. 3j., Bole Armen. 3j., Calomel 3j., Adipis 3iv., M. It should be applied to the lids with the finger or a camel's-hair brush. The simple ointment (ante) is also an excellent application.

2849. In Gonorrhoea and Leucorrha, Somme successfully employed an injection of the Oxide (ss. ad Aq. Oij.).

2850. To Ulcers On The Nipples,

Dr. Bochm,§ of Berlin, advises a powder, composed of 1 part of the Oxide and 2 of powdered Gum Arabic, to be sprinkled on the sores. It forms a thin crust over the ulcerated surface, which, being thus protected, speedily heals. To Bed Sores and superficial Excoriations, &c., the Ung. Zinci (ante) is a good and efficient application.

2851. In Scrofulous Coryza and Ozna, the local application of the ointment is very serviceable. Dr. Willshire|| directs that it should be introduced into the nasal cavity, by means of a camel's-hair brush, every night and morning. The patient should be put, at the same time, under a course of Iodine, Quinine, or Iron, and the bowels regulated by Rhubarb and Soda.

2852. In Skin Diseases, particularly in Eczema, Ecthyma, Por-rigo Larvalis, and Porrigo Furfurans, Martin-Solon ¶ found an ointment, composed of gr. xv. - xlv. of the Oxide and gr. xxx. of Lard, of signal benefit. In Eczema, Dr. T. McCall Anderson** recommends a mixture of powdered Oxide of Zinc (ss.) and

* Trans. of Med.-Chir. Soc, vol. iii. Lancet, April 2, 1859. Archiv. Gen. de Med., vol. i p. 846. § Med.-Chir. Rev., No. lviii.

|l Clin. Lect., Med. Times, vol. xviii. p. 151.

¶ British and Foreign Med. Rev., vol. xxvi. p. 541.

** Med. Times and Gaz., July 11, 1863.

Glycerine (fij.) as a very soothing application. Its efficacy is increased by the addition of a little Camphor. In Chronic Impetigo, Dr. Watson* speaks highly of the Oxide of Zinc. He advises its being dusted over the affected surface, or applied in the form of lotion (gr. xv. ad Aq. fj.). This he also found particularly useful in Crusta Lactea. He objects to the use of ointments. In Lichen Agrius, Erythema, and Sycosis, it is advised by E. "Wilson.