Dr. Jacob observes, that in order to secure a full exposure of the whole conjunctiva of both the eye and the lids to the contact of the fluid, it should be introduced beneath the upper lid at the outer angle, by separating the two surfaces, and introducing a large drop, from a full-sized camel's-hair pencil, between them. By laying the thumb or finger on the skin between the lid and the brow, and pushing it up over the margin of the orbit, a space is made between the lid and ball, into which the fluid should be dropped; and from this it will spread over the whole surface. If a more complete saturation of the upper lid be required, it must be everted, and repeatedly brushed over with the solution.

3048. Observations On Their Use

1. Collyria, particularly the stronger ones, should not be employed indiscriminately; they are often, not only unnecessary, but absolutely mischievous.

2. It is the opinion of many of the best oculists of the day, that the employment of collyria of a strength to cause pain in the eye tends to induce subsequent chronic inflammation. 3. Those containing Lead should never be employed when ulceration of the cornea exists, as it is apt to leave a permanent opaque cicatrix. 4. Those containing Nitrate of Silver sometimes cause a blackish or bluish discoloration of the conjunctiva.