The only or principal disease in which these are employed is Gonorrha; and even here much difference of opinion exists as to their safety and efficacy, one class denouncing them as the origin of Orchitis, inflammation of the bladder, stricture, &c, and another class regarding them as safe and efficacious. The fact of the matter appears to be, that if a strong solution (Argent. Nit. gr. x., Aq. fl. oz. j.) of a salt be injected at the very outset of the disease, before scalding in making water has come on, the danger is comparatively slight; although, it must be admitted, that even under these favourable circumstances, untoward accidents do occasionally occur. If, on the other hand, the disease has progressed and inflammatory action be established, the same injection is fraught with the greatest danger. When, however, the inflammation has subsided, and the disease passes into a chronic state, injections, weaker than that above mentioned, may be had recourse to with advantage.

Urethral injections may be divided into Irritant, Sedative, Emollient, and Astringent. Irritant Injections, as solutions of Corrosive Sublimate, Nitrate of Silver, &c, should never, observes Mr. Samuel Cooper, be used when there is considerable inflammation present; nor should they be used when the inflammation has spread beyond the specific disease; nor when the disease ceasing quickly, these parts have become sore; nor when the perineum is very susceptible of inflammation; nor when there is a tendency in the bladder to irritation, known by the frequency of passing urine. In mild cases and in constitutions which are not irritable, these injections often succeed, and remove the disease immediately. Sedative Injections, composed of Opium or Liq. Plumbi, give generally great relief in irritable constitutions, but they do nothing towards effecting a cure of the disease. The same observation applies to Emollient Injections, Astringent Injections are often very serviceable in the third stage of Gonorrhoea, or when it is degenerating into a gleet. Decoctions of Oak-bark, Galls, &c, or solutions of Alum, form the principal of these.

3169. Observations On Their Use

1. An injection should never be used so strong as to cause anything like severe pain in the urethra. (Graves.*)

2. Always desire the patient before using it to void a little urine, in order to clear the urethra of any mucus, &c, which would otherwise prevent the fluid coming in contact with the lining membrane.

3. The point of the syringe must be carefully introduced, at least half an inch within the lips of the urethra; and care should be taken that the point be not hitched in a fold of the membrane lining the urethra.

4. When the point of the syringe is withdrawn, the lips of the urethra should be kept closed with the finger and thumb for two or three minutes, when the fluid may be allowed to escape.

5. In employing caustic injections at the commencement of an attack of Gonorrhoea, Mr. Acton directs that the patient should not pass urine immediately after their use, and that he should lie down for half an hour or so.

6. It is of importance to remember that the Sulphates of Copper, Zinc, and Alum, which coagulate albumen when used in moderate proportions, re-dissolve it when employed too strong, and may thus tend to keep up the discharge. The Nitrate of Silver in small quantities coagulates the albumen; in large ones, it combines with it, and cauterizes the tissues.

7. Injections should not be trusted to alone for the cure of Gonorrha; Copaiba, Cubebs, aperients, and an antiphlogistic regimen should be used as auxiliaries.

8. When One Kind Of Injection Fails, Another Often Succeeds

9. A glass syringe is always preferable to a metal one, as the latter is apt to form compounds with the solution used, and to become coated with dirt.