In Tic Douloureux, and Neuralgia, arising from Dyspepsia, and also in that connected with disorders of the Uterus, Mr Hunt states that he has derived the greatest amount of benefit from Arsenic, in combination with a sedative, commencing with about eiv. of Liq. Arsenicalis, and daily increasing the dose, till some decided symptom of its action is perceptible, which is commonly evinced when the dose has amounted to 10 drops. He adds, that " Arsenic operates most favourably on persons who are of lax fibre, accompanied by a languid state of the circulation, and whose secretions are rather profuse than otherwise, the urine pale and plentiful; and, more especially, on those whose skins are cold and moist. In persons of this description, Arsenic, far beyond other medicines, relieves the neuralgic pains, improves the general health, and gives firmness to the constitution" In Neuralgia arising from Spinal disease, or AnAemia, Arsenic is positively hurtful; and in that occurring in plethoric subjects, it is productive of little good.
* Treatise on Intermittent Fevers, 8vo. Paris, 1842, pp. 276 - 2S0. Gaz. des. Hop. 1856, No. 113.
On Tic Douloureux, Svo. Lond. 1844, p. 174.
Dr. Watson* speaks favourably of it. He believes that gutt. iv. - vj. of Liq. Arsenicalis, three or four times a day, with due attention to the state of the bowels, will be almost sure to remove Hemicrania, in nine cases out of ten.
Dr. Fuller remarks that Arsenic, judiciously administered and carefully watched in its effects, is one of the most valuable remedies we possess in the chronic forms of this disease. Dr. Christison also bears witness to its efficacy; and Dr. Begbie, who entertains a high opinion of it, relates several cases illustrative of the benefit to be derived from it. Dr. Begbie regards Arsenic as a special alterative in the rheumatic diathesis - a true antirheumatic. M. Gueneau de Mussy speaks of the great benefit derivable from Arsenical baths in Rheumatic Gout. To each bath he adds Carb. of Soda iij.ss. and Arseniate of Soda gr. xv. gradually increased to gr. xxx. These, however, failed in the hands of M. Trousseau.§ In Rheumatic Gout, especially when characterised by extreme inactivity of the skin, which is cold, harsh and dry, Arsenic is very favourably spoken of by Dr. Fuller. || If the urine be turbid, he gives Liq. Arsenicalis eviij. - xv. with Liq. Potass. or Potass. Acet.*; if the urine be clear and of a low sp. gr., he gives Liq. Arsen. Chlorid. e.x. - xx. either alone or with bark; and if acids be indicated, with Hydrochloric Acid.
Stokes¶ and others, with decided success. He recommends 1/20 of a grain of Arsenious Acid, to be combined with a small portion of Morphia and Creosote. This is applied on a small piece of cotton wool to the sensitive part of the tooth, and retained in situ by a bit of soft wax. Mr. Stokes adds, that he knows of no remedy of equal efficacy and certainty, and that it may be regarded almost in the light of a specific. A similar application (having an addition of Pulv. GallAe gr.1/4) is also strongly recommended by Dr. Castles,** of New York.
* Lectures, vol. i. p. 718. Edin. Mel. Journal, May 1858, p. 961. Gaz. des Hopitaux, Aug., 1861. § Journ. do Med. Prat., Kov. 1861.
II Brit. Med. Journ., March 28, 1857. ¶ Med. Times, April 14, 1849. ** Lancet, March 25, 1843.