Chloride of Barium. BaCl + 2HO. Muriate of Barytes. A compound of Barium 56.326, Chlorine 28.980, Water 14.964, in 100 parts; or 1 Eq. of Barium = 69 + 1, Chlorine = 35.5 + 2, Water = 18 = 122.5, Eq. Wt.
Med. Prop. and Action. For internal use, this salt should be given in the form of solution (Barii Chlor. gr. lx., Aq. Dest. fl oz. j., dissolve and strain). In small doses, gutt. viij. - x. of the solution, it is stimulant, tonic, alterative, and resolvent; in large doses, a powerful acrid, irritant poison. Its use requires great caution, and it should always be commenced in the smallest dose, and gradually increased, as the patient is able to bear it. If nausea, or purging, or giddiness ensue, the dose should be decreased, or the remedy relinquished altogether. Under its use, the appetite increases, there is augmented secretion of urine, and slight diaphoresis, at the same time that the general health improves. A very instructive case, showing the danger of large doses, is related by Dr Fergusson,* of Dublin. In large doses, it manifestly affects the brain and nervous system, and causes death by its action on those parts, and on the heart.
Dose, gr. 1/2 to gr. j., or gr. ij.
In Scrofula, it was proposed as a remedy by Crawford, and was employed with success by Pinel, Hufeland,§ and others; whilst, in the hands of Mr. Burns and Dr. Thompson, it was productive of slight benefit. The danger which occasionally attends its use has been the chief reason of its not having come into general use. Mr. R. Philips || prefers it in many cases to Iodine, and states that where the tallow-like complexion, the pale tongue, and languid circulation, accompanied by irritability of the mucous surfaces, are present, the virtues of the Chloride of Barium are often remarkably demonstrated Mr. Balman* entertains a very favourable opinion of its efficacy, particularly in chlorotic, cachectic, and other cases attended with a languid circulation and much general debility. He considers, therefore, that it is well adapted for females of a lymphatic temperament, and attended with any irregularity of the menstrual functions. In such cases, he advises the following formula: -
Barii Chlor. gr. x., T. Ferri Sesquichlor. f3ij. - fss., Syr. Aurant. vel Aq. Dest. fx., M. Dose, fss. - fj. twice or thrice daily.
* Dublin Quart. Journ., Feb. 1,1844. Medical Communications, vol. ii. Nosograph. Philos., vol. ii. p. 372.
§ Journ. der Pr. Heilk. b. vii. st. 3 || On Scrofula, 8vo, Lond. 1846.
Torget speaks highly of its employment. He considers it a most valuable remedy, and believes that, in some cases, it has alone sufficed to effect a cure, whilst the majority of cases were greatly relieved by its use. He advises it in considerable doses, and to be persevered in for a month. In Epilepsy and Headaches occurring in connection with Scrofula, it is spoken of very favourably by Hufeland; and in Scrofulous Ophthalmia, it has been used by Dr. Pay, § of Aix in Provence, internally as well as locally, as a collyrium For the latter purpose, it should be largely diluted. In Tetanus it has been successfully employed by Dr. Gnecchi || of Milan; he employed gr. xvj. dissolved in Oj. of water, taken in divided doses in the twenty-four hours.